摘要
[目的]探索生活和工作环境中胚胎停育的危险因素,特别是职业紧张与胚胎停育的关系。[方法]采用病例-对照研究对267例胚胎停育患者和285例正常妊娠分娩者进行问卷调查,对相关数据进行X^2检验、t检验与非条件Logistic回归分析。[结果]年龄、体育锻炼、使用手机和电脑的时间、装修、通风、补充叶酸、偏爱煎炸食品、生殖知识、婚检、产次、计划受孕时间和职业紧张在病例组与对照组存在差异(P<0.05),Logistic回归表明体育锻炼(OR=0.319)、通风(OR=2.496)、补充叶酸(OR=2.365)、年龄(OR=1.106)和职业紧张(OR=2.159)进入方程。[结论]体育锻炼、居室通风、补充叶酸是预防胚胎停育的保护性因素,高龄和职业紧张是危险因素。日常生活和工作环境中除传统的物理、化学、生物因素外,精神因素和生活习惯的作用越来越突出,在保健和预防中值得关注。
[ Objective ] To investigate the potential factors which related to the induction of embryo damage in living and working environment, especially the relationship between occupational stress and embryo damage. [ Methods ] 267 Cases and 285 controls were investigated by case-control study, the data were analyzed by X^2 test, t-test and logistic regression respectively. [ Results ] The factors including age, exercise, the exposure time to cell phone and computer, refurnishing houses, ventilation, supplementary of folic acid, favoring frying food, reproductive knowledge, premarital consultation, parity, the opportunity of plan for conception and occupational stress were significant different between case and control groups （ P 〈 0.05 ）. Logistic analysis revealed that exercise （ OR=0.319 ）, ventilation （ OR=2.496 ）, supplementary of folic acid （ 0R=2.365 ）, age （ OR=1.106 ）and occupational stress （ 0R=2.159 ）were in the regressive model. [ Conclusion ] Exercise, ventilation and supplementary of folic acid were the protective factors to prevent embryo damage. Advanced age for pregnancy and occupational stress were the risk factors for embryo damage. Besides traditional physical, chemical and biological factors, living habits and psychological factors are more and more important in health care and prevention.
出处
《环境与职业医学》
CAS
北大核心
2008年第4期346-350,共5页
Journal of Environmental and Occupational Medicine
关键词
胚胎停育
职业紧张
环境
危险因素
embryo damage
occupational stress
environment
risk factor
