摘要
目的了解结核菌-L型在复治难治(复难治)肺结核患者中所占的比例,以及对结核病疫情的影响。方法选择复难治肺结核患者现场拍摄X光胸片,晨痰作结核菌和结核菌-L型培养。结果在260例复难治肺结核患者痰标本中,检出结核菌阳性92例;92例结核菌阳性患者中,检出结核菌-L型阳性32例,检出率为34.8%。168例结核菌阴性患者中检出结核菌-L型阳性45例,检出率为26.8%。结核菌和结核菌-L型均阳性的患者,其X光胸片病变范围比结核菌和结核菌-L型均阴性的患者广泛(x^2=6.44,P<0.05);其肺部空洞也明显增多(x^2=31.63,P<0.01)。结论无论是菌阳还是菌阴结核病患者,都可检出结核菌-L型;结核菌和结核菌-L型合并感染,可导致患者双侧肺病变加重、空洞增多。
Objective To investigate the ratio of L-form of Mycobacterium tuberculosis （TB-L） infection in recurrent pulmonary tuberculosis（TB） patients and its effect to pulmonary lesions and epidemic situation of tuberculosis. Methods The X-ray chest films of the recurrent pulmonary tuberculosis patients were photographed in situ and analyzed, and the patients＇ morning sputum were cultivated for TB and TB-L. Results There were 92 TB-positive cases in 260 recurrent pulmonary tuberculosis patients. In 92 TB-positive cases, 32 TB-L positive cases were detected with positive detection rate of 34. 8%. There were 45 TB-L positive cases in 168 recurrent pulmonary tuberculosis patients whose sputum were tuberculosis negative and the TB-L positive detection rate was 26.8 %. The data also demonstrated that the pulmonary lesion extent of both TB and TB-L detection positive patients was more extensive than those both negative patients （ X^2 = 6.44, P 〈 0. 05 ）. Additionally pulmonary cavity significantly increased in both TB and TB-L detection positive patients （X^2 = 31.63, P 〈 0. 01 ）. Conclusion These results suggest that TB-L could be detected in TB positive or TB negative patients. TB co-infection with TB-L may aggravate bilateral pulmonary lesions and increase cavities. There are 26. 8% TB-L positive patients＇in TB negative patients, therefore their treatment and impact on epidemic situation should no be, igrored.
出处
《预防医学情报杂志》
CAS
2008年第9期706-707,共2页
Journal of Preventive Medicine Information
关键词
结核菌-L型
肺结核
感染者
分析
L-form of Mycobacterium tuberculosis
Recurrent pulmonary tuberculosis
Infection
Analysis.
