摘要
目的探讨肾移植患者手术前后尿液中IL-6的变化及临床意义。方法采用ELISA法,动态监测患者移植手术前后尿液中IL-6的浓度。结果尿液中IL-6的浓度在肾移植术后第1天明显升高。急性排斥反应前1~2天尿液中IL-6的浓度有不同程度的升高,抗排斥治疗后迅速下降。结论动态监测尿IL-6是早期诊断肾移植术后急性排斥反应的一个较好的参考指标。
Objective To investigate the change of urinary interleukin-6 in the receptors after renal transplantation and to evaluate its contribution to predict acute rejections. Methods The urinary interleukin-6 were detected by enzyme linked immunosorbent assay(ELISA) and its clinical significance was analyzed combined with occurrence of acute rejections. Results Urinary interleukin- 6 1 day after transplantation in all receptors was higher than that before transplantation and its level began increasing 1-2 days before acute rejection(P〈0.01). Conclusion Urinary interleukin-6 may play significant role for the prediction of the rejections and the increased survival rate of graft.
出处
《重庆医学》
CAS
CSCD
2008年第17期1960-1960,1963,共2页
Chongqing medicine