摘要
目的探讨急诊控制快速型心房颤动心室率之安全有效药物。方法将57例心房颤动、心室率>120次/min 的患者分为:A、美托洛尔,B、维拉帕米,C、普罗帕酮,D、毛花苷丙,E、胺碘酮5组。多参数生命体征监护下静脉注射给药;设定心室率100次/min 以下为目标,观察达标时间。结果 A 组(4.0±1.62)min,B 组(7.17±2.64)min,C 组(9.90±3.59)min,D 组(57.67±34.97)min,E 组(107.40±49.98)min 达到预定心室率范围。结论心房颤动就迅速控制心室率而言,美托洛尔、维拉帕米、普罗帕酮3者的速度依次减慢,但3者差别没有统计学意义;而毛花苷丙和胺碘酮速度显著慢于前3种,差别有统计学意义。
Objective To find an efficiency and safe medicine for emergency control of the fast atrial fibrillation patient' s ventricular rate. Methods Dividing 57 patients whose ventricular rate 〉 120/min to 5 groups: A, metoprolol; B, erapamiy; C, proafenone; D, lanatoside ; E, aminodaron, setting 〈 100/min as the sign of getting normal ventricular rate and according the time to this level of each group. Results It took group A : ( 4. 0±1.62) min, group B: ( 7. 17±2. 64) min, group C : (9. 90±3.59) min, group D : ( 57.67±34. 97) min, group E : ( 107. 40±49. 98) min to reach the normal ventricular rate. Conclusion As to the speed of controlling the ventricular rate. The metoprolol, verapamiy and proafenone are less effective one by one, but there had no statistical significance. The lanatoside and aminodaron were much slower and the different was statistical significantly.
出处
《临床急诊杂志》
CAS
2008年第3期169-171,共3页
Journal of Clinical Emergency
关键词
心房颤动
控制心室率
Atrial fibrilation
Control of the ventricular rate