摘要
小鼠在正常状况下仅有撕咬垫料行为，在饥饿状态下少量嚼食薄草垫料，但不引起小鼠中毒。急性毒性试验表明，蒲草的水浸出物，醇浸出物，醚浸出物的ＬＤ５０分别大于蒲草２２．４、１５．７、１９．６ｇ／ｋｇ体重，灌胃后小鼠行为、反应正常，无中毒症状。４日后处死剖检结果，脏器亦无病变。大鼠经皮肤涂抹浸出物（每次剂量分别相当于蒲草７６．０、５３．３、６６．７ｍｇ／ｃｍ２，重复３次）后，无全身中毒症状，涂抹部位无临床上肉眼可见病变。兔滴眼试验（每次剂量分别相当于蒲草１２８．５、９０．２、１１２．７ｍｇ／ｋｇ体重，重复３次）证明，眼无临床上肉眼可见病变。大鼠经口及兔经皮试验亦得到相同结果。说明蒲草垫料的三种浸出物对动物无毒害作用。
Mouse only has behaviur of tearing bedding at the nomalpresent,and eats cattails at the starvation present.But that smallamounts of things doesn't lead marine to toxicity.Acute toxicityexperiment showed that LD50 of extractions of water,alcohol and othersof cattailwere nore than 22.4,15.7,19.6 g cattail/kg body weight,respectively.The behaviour and reaction of mouse,after clyster werenormal,had no toxicity symptom.Organs of slaughted mouse after 4 dayshad no lesion either.Mice had no toxicity sympton by applyingextractions on their skin(each dse were equal to 76.0,53.3,66.7 mgcattail/cm,respectively,repeated 3 times).The lesion was invisible tonaked eye on the applied place.Rabbits were dropped with extractonsshowed there was no visible lesion to naked eyes,too.Murine by mouthand rabbit by skin had the same results.It indicated that the 3 kindsof extractions had no toxicity to the animals.
出处
《黑龙江畜牧兽医》
CAS
北大核心
1997年第12期6-8,共3页
Heilongjiang Animal Science And veterinary Medicine
基金
黑龙江省科技计划项目
