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心脏再同步化治疗远期疗效观察

The Long-term Effects of Cardiac Resynchronization Therapy in Congestive Heart Failure
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摘要 目的:观察7例充血性心力衰竭患者心脏再同步化治疗远期疗效。方法:应用三腔心脏起搏器对有适应症[心脏彩超EF〈35%,左室舒张末容积〉50mm,二尖瓣有中到大量返流,心电图有完全性左束支或室内阻滞,有反复心功能不全(NYHAⅢ~Ⅳ级)病史]的患者分别将左室电极送入左室侧支,右室、右房电极常规植入,术后观察12个月心脏功能。结果:7例患者临床症状均有明显改善。尤其第一年后EF值、LVEDD,差别有显著性,P〈0.05。结论:慢性充血性心力衰竭患者采用CRT治疗比单纯性药物控制效果满意,可明显改善心脏功能。 Objective:To assess the long- term effects of cardiac resynchronization therapy (CRT) in 7 patients with congestive heart failure (CHF). Methods :Applying triple chamber cardiac pacemaker ( bi -ventricular pacing) to treat the patients who had left ventricular ejection fraction(LVEF) below 35%, left ventricular end diastolic diameter( LVEDD)were over 50mm , moderate to huge mistral regurgitation in echocardiography, complete left bundle branch block(CLBBB) or intra -ventricular conduction delay in electrocardiogram, the history of repeated cardiac insufficiency( NYHA Ⅲ-Ⅳ ). Good parameters were obtained in each patient. Left ventricular pacing lead were inserted into left ventricular venous branch of the coronary sinus, then right ventricular pacing lead and right atria pacing lead were implanted by routine methods . The cardiac function of all patients was observed for 12 months after operation. Results:The clinical symptoms of those seven patients have obviously improved, especially the patient' EF, LVEDD (P 〈 0.05) were remarkably improved within the first year after the operation. Conclusions:The CRT has reached satisfactory results, and it can improve cardiac function significantly in the patients with congestive heart failure compared with medical therapy only.
出处 《青海医药杂志》 2008年第8期2-4,共3页 Qinghai Medical Journal
关键词 心脏起搏 充血性 再同步化治疗 心力衰竭 Cardiac pacemaker Congestive heart failure Resynchronization Therapy
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