外源化学物对DNA甲基转移酶的调控
出处
《毒理学杂志》
CAS
CSCD
北大核心
2008年第4期313-316,共4页
Journal of Toxicology
基金
国家自然科学基金重点项目(30630055)
国家自然科学基金973计划项目(2002CB512903)
参考文献18
-
1Jaenisch R, Bird A. Epigenetic regulation of gene expression how the genome integrates intrinsic and environmental signals Nat Genet, 2003, 33 Suppl: 245-254.
-
2Fuks F. DNA methylation and histone modifications: teaming up to silence genes. Curr Opin Genet Dev, 2005, 15: 490- 495.
-
3Belinsky SA. Silencing of genes by promoter hypermethylation : key event in rodent and human lung cancer. Carcinogenesis, 2005, 26: 1481-1487.
-
4Goll MG, Bestor TH. Eukaryotic cytosine methyltransferases. Annu Rev Biochem, 2005, 74: 481-514.
-
5Chen RZ, Pettersson U, Beard C, et al. DNA hypomethylation leads to elevated mutation rates. Nature, 1998, 395: 89-93.
-
6Okano M, Xie S, Li E. Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells. Nucleic Acids Res, 1998, 26: 2536-2540.
-
7Okano M, Bell DW, Haber DA et al. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell, 1999, 99: 247-257.
-
8Rhee I, Bachman KE, Park BH, et al. DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature, 2002, 416: 552-556.
-
9Matsuzaki KDG, Deng G, Tanaka H, et al. The Relationship between global methylation level, loss of heterozygosity, and microsatellite instability in sporadic colorectal cancer. Clin Cancer Res, 2005, 11 : 8564-8569.
-
10Sato K, Fukata H, Kogo Y, et al. Neonatal exposure to diethylstilbestrol alters the expression of DNA methyhransferases and methylation of genomic DNA in the epididymis of mice. Endocr J, 2006, 53: 331-337.
-
1张铣.外源化学物对钙调素的影响[J].卫生毒理学杂志,1997,11(4):266-269. 被引量:2
-
2胡艳玲,傅得兴,胡欣.地西他滨的药理作用和临床评价[J].中国药学杂志,2008,43(2):81-84. 被引量:6
-
3张海洲,张铣,薛彬.外源化学物免疫抑制机理的研究进展[J].国外医学(卫生学分册),1996,23(5):260-263.
-
4吴圣豪,郑翠苹,徐杰.硼替佐米对K562细胞株DNA甲基转移酶表达的影响[J].海峡药学,2012,24(12):276-278.
-
5郭尧平,农清清,范誉,韦宏旷,何灏逾,胡新梅,廖娟,陆继培.微囊藻毒素-LR对小鼠肝细胞DNA甲基化的影响[J].环境与健康杂志,2014,31(10):906-909.
-
6凌晓璇,梁海荣,黄明元,杨慧,唐焕文.氢醌对DNA甲基转移酶表达的影响[J].实用预防医学,2012,19(7):961-963. 被引量:2
-
7殷宏,金涌,邢仕歌,田世民.外源化学物的表观遗传毒性及其安全性评价[J].毒理学杂志,2010,24(6):487-491. 被引量:1
-
8姜绮霞,袁洪.脱氧核糖核酸甲基化抑制剂的研究进展[J].中国新药与临床杂志,2007,26(10):789-793. 被引量:1
-
9叶静娴,鹿全意.组蛋白去乙酰化酶抑制剂治疗血液肿瘤研究进展[J].中国临床药理学杂志,2010,26(10):777-780. 被引量:1
-
10Thomas,F.Bumol,徐世淞,等.遗传信息、基因组技术和药物发展的未来[J].美国医学会杂志(中文版),2001,20(6):275-278. 被引量:1