摘要
目的探讨原发性肝癌术后经肝动脉化疗栓塞对患者复发率及生存率的影响。方法对2003年至2006年本院行肝癌切除术后的156例患者,按术后1个月左右是否补充介入治疗分为TACE组(88例)和对照组(68例),对比分析两组患者术后1、2、3年的累积复发率和生存率。结果TACE组1、2、3年的累积复发率分别为12.1%、48.6%、74.6%,累积生存率分别为83.0%、72.8%、63.2%;对照组1、2、3年的累积复发率分别为46.9%、65.5%、82.7%,累积生存率分别为72.6%、58.3%、51.0%。两组间比较差异有显著性(P<0.05)。结论术后予辅助性肝动脉化疗栓塞可降低患者复发率,延长生存期。
Objective To evaluate the effect of post-operative TACE on recurrence and survival rate after hepatocellular carcinoma（HCC） surgical resection. Methods From 2003 to 2006,156 cases received resection of HCC. They were divided into TACE group （88 cases） and control group （68 cases ） . Patients in TACE group were given adjuvant interventional therapy about 1 month after operation. Patients in control group did not receive TACE. Post-operative 1 - 3 year cumulative recurrence rate and survival rate were analyzed comparatively. Results The 1 - 3 year cumulative recurrence rate in TACE group were respectively 12.1% ,48.6% and 74.6% , the survival rate were 83.0% , 72.8% and 63.2%. Meanwhile, those in control group were respectively 46. 9% , 65.5% and 82.7%, the survival rate were 72.6%, 58.3% and 51.0%. There was significant difference between TACE group and control group （ P 〈 0.05 ）. Conclusion Adjuvant TACE after HCC surgical resection can reduce recurrence rate and prolong survival time.
出处
《微创医学》
2008年第5期417-419,F0003,共4页
Journal of Minimally Invasive Medicine
基金
福建省科技厅资助青年人才项目(2006F3035)
关键词
癌
肝细胞
化疗栓塞
预后
Carcinoma
Hepatocellular
Chemoembolization
Prognosis
