期刊文献+

阿托伐他汀与阿司匹林联用对家兔血小板聚集作用的影响

下载PDF
导出
摘要 目的:研究阿托伐他汀(atorvastatin,ATV)与阿司匹林(aspirin,ASA)联用对花生四烯酸(arachidonicacid,AA)和二磷酸腺苷(adenosine diphosphate,ADP)诱导的家兔血小板聚集作用的影响。方法:运用比浊法原理,经TYXN-96型多功能智能血液凝聚仪测定ATV与ASA单用及联用对家兔血小板聚集作用的影响。结果:ATV与ASA均能抑制AA和ADP诱导的离体和在体家兔血小板的聚集,且ATV和ASA联合应用抑制作用更强。结论:ATV和ASA联用可增强对AA和ADP诱导的家兔血小板聚集的抑制作用,提示临床联用这些药物治疗血栓等栓塞性疾病或使用其复方制剂可能具有更好的效果。
出处 《亚太传统医药》 2008年第9期35-37,共3页 Asia-Pacific Traditional Medicine
  • 相关文献

参考文献3

二级参考文献33

  • 1侯金玲,吴葆杰,延汝谦.烟酸和阿司匹林合用对大鼠血浆脂质的调整作用[J].山东医科大学学报,1993,31(1):30-33. 被引量:12
  • 2刘洪海,吴越,张梅,丁一上,杨德林.烟酰水杨酸的合成及调血脂作用初步研究[J].石河子大学学报(自然科学版),2004,22(6):483-486. 被引量:19
  • 3Knight CJ. Antiplatelet treatment in stable coronary artery disease [ J ].Heart,2003,89(10): 1273.
  • 4Kearney D, Byrne A, Crean P, et al. Optimal suppression of thromboxane A2 formation by aspirin during percutaneous transluminal coronary angioplasty: no additional effect of a selective cyclooxygenase-2 inhibitor[ J]. J Am Coll Cardiol,2004,43(4) :532.
  • 5Herlitz J, Holm J, Peterson M, et al. Effect of fixed low-dose warfarin added to aspirin in the long term after acute myocardial infarction; the Lo WASA Study[J] .Eur Heatr J,2004,25(3) :232.
  • 6Zibaeenezhad MJ, Mowla A,Sorbi MH.Warfarin and aspirin versus aspirin alone in patients with acute myocardial infarction :a pilot study[ J].Angiology, 2004,55(1) :17.
  • 7Belanger P, Palisaitis DA, Diodati JG, et al. Effects of high ticlopidine doses on platelet function in acute coronary ayndrome patients[J] .J Cardiovasc Pharmacol, 2004,43 ( 1 ): 128.
  • 8Lindgren P,Jonsson B,Yusuf S. Cost-effectiveness of clopidogrel in acute coronary syndromes in Sweden: a long -term model based on the CURE trial[J] .J Intern Med,2004,255(5) :562.
  • 9Exaire JE Dauerman HL, Topol EJ, et al. Triple antiplatelet therapy does not increase femoral access bleeding with vascular closure devices[J].Am Heart J,2004,147(1) :31.
  • 10Massberg S, Mueller I, Besta F, et al. Effects of 2 different antiplatelet regimens with abciximab or tirofiban on platelet function in patients undergoing coronary stenting[J] .Am Heart J,2003,146(5) :E19.

共引文献12

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部