摘要
目的比较复方白松片和氟西汀治疗抑郁症的临床疗效及不良反应。方法将59例抑郁症患者随机分成两组:白松片治疗组29例,给予复方白松片口服;氟西汀对照组30例,给予氟西汀胶囊口服,两组疗程均为6周。治疗前及治疗后2,4,6周末采用汉密尔顿抑郁量表(HAMD)和不良反应量表(TESS)评定西医临床疗效和不良反应,并采用"中医肝脏象情绪量表"评定中医疗效。结果两组治疗结束时HAMD评分均有显著下降(P<0.01),治疗组总有效率为68.9%,对照组总有效率为70.0%,两组疗效及不良反应比较差异无统计学意义(P>0.05)。结论白松片是一种安全有效的抗抑郁中药复方。
Objective To compare the effect and security of compound Baisong tablets and Fluoxetine in treating depression. Methods 59 patients with depression were randomly divided into two groups and treated with Baisong tablets for 29 patients in group A, and Fluoxetine capsule for 30 patients in group B respectively. The western medicinal clinical efficacy and side effects were evaluated with Hamilton's depression scale(HAMD) and treatment emergent symptom scale(TESS) respectively, and the Chinese medicine efficacy were evaluated with an emotion rating scale for Ganzangxiang(ERSG) of traditional Chinese medicine(TCM) after 2, 4 and 6 weeks treatment respectively. Results The scores of HAMD between the two groups decrease notably after ending the treatment (P〈0.01), The total efficient of group A was 68.9%, while that of group B was 70.0%, the effects and side effects between the two groups was not differences. Conlusions Baisong tablets is a safe and effective in treating depression.
出处
《湖南中医药大学学报》
CAS
2008年第4期48-49,56,共3页
Journal of Hunan University of Chinese Medicine
基金
湖南省卫生厅中医药科研基金资助项目(24202)