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女童解脲支原体感染状况调查分析 被引量:3

A investigation and analysis of ureaplasma urealyticum infection of female children
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摘要 目的调查解脲支原体致女童泌尿生殖道感染情况分析。方法对2005年9月~2008年6月在西安市儿童医院因阴道炎就诊女童的阴道分泌物做定量PCR检测,并对解脲支原体-DNA阳性患儿的临床特点进行回顾性分析。结果274例阴道炎女童解脲支原体-DNA阳性31例,感染率为11.3%,其中〈3岁者1例,4~7岁者12例,8~12岁者18例,各年龄组间发病率比较无显著性差异(χ^2=5.89,P〉0.05)。患儿主要临床表现为阴道分泌物增多且呈黄绿色,尿频、尿痛、外阴不适。应用红霉素、中药(苦参洗剂)坐浴,痊愈。结论解脲支原体主要引起女童泌尿生殖道感染。阴道分泌物定量PCR检测解脲支原体-DNA可辅助临床诊断。 Objective To investigate prevalence of ureaplasma urealyticum (Uu) infection of female children. Methods The clinical features and quantitative PCR detection result of vaginal secretions of 274 girls aged 1 - 7 years old with vaginitis admitted to Xi' an Municipal Children' s Hospital were analyzed retrospectively. Results Among 274 girls with vaginitis, Uu - DNA of 31 girls was positive, the infection rate was 11.3%, including lgirl aged under 3 years old, 12 girls aged4 -7 years old and 18 girls aged 8 - 12 years old. In incidence rate of the disease, there was no significant difference between different age groups ( χ^2 = 5.89, P 〉 0.05 ). The main clinical manifestations of children with vaginitis included increased yellow-green vaginal secretions, frequent micturition, odynuria and vulval indisposition. All children were treated with erythromycin and kusheng lotion hip bath and cured. Conclusion Uu mainly causes genitourinary tract infection of female children. Quantitative PCR detection of Uu - DNA for vaginal secretions is helpful for diagnosis of the disease in clinic.
机构地区 西安市儿童医院
出处 《中国妇幼健康研究》 2008年第5期518-519,共2页 Chinese Journal of Woman and Child Health Research
关键词 女童 解脲支原体 泌尿生殖道感染 回顾性分析 female children ureaplasma urealyficum (Uu) genitourinary tract infection retrospective analysis
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  • 1Shrier L A, Dean D, Klein E, et al. Limitations of sereening tests for the detection of Chlamydia trachomatis in asymptomatic adolescent and young adult women [ J ]. Am J Obstet Gynecol,2004,190(3) :654-662.
  • 2陈东科,高洁,宣天芝.非淋菌性尿道炎支原体感染率调查及耐药性分析[J].中华医院感染学杂志,1999,9(2):123-124. 被引量:37
  • 3Li H, Dummer J S, Estes W R, et al. Measurement of human cytomegalovirus loads by quantitative real-time PCR for monitoring clinical intervention in transplant recipients [J]. J Clin Microbiol, 2003,41 ( 1 ) : 187-191.

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