摘要
目的本文通过探讨单纯性肥胖儿童的体重、血压、血脂、动脉内膜的变化及干预治疗的影响,发现早期病变,进行早期干预治疗。方法采用高分辨率彩色多普勒超声检测仪检测肥胖组干预治疗前后和对照组动脉内膜-中层厚度(IMT)和血流速度(PSV和EDV),并检测血压、血脂。肥胖组给与综合干预治疗。结果肥胖组儿童动脉内膜呈现出不同程度的毛糙、不光滑、连续性差、限局性增厚的回声,有的甚至形成局部强回声斑块,动脉IMT均值明显高于对照组(P<0.001),肥胖组血压升高(P<0.01),甘油三脂(TG)、总胆固醇(TC)升高(P<0.001)。干预治疗后动脉内膜变化明显改善,与干预前对比IMT厚度降低(P<0.01)。结论中、重度单纯性肥胖儿童已经不同程度的出现心血管系统的改变,早期干预治疗可阻止病变进一步发展。
Objective Based on the simple obesity children＇s weight,blood pressure,serum lipids,artery intimal changes and the impact of intervention treatment, to detect early disease and give early intervention therapy. Methods In the obesity group and the control group,had used high-resolution color Doppler ultrasonic to test the artery intima-media thickness （IMT） and the blood velocity （PSV and EDV） ,and measured blood pressure,blood lipids,the obesity group had been measured before and after the intervention treatment. The obesity group were given comprehensive intervention treatment.Results In obesity group,artery intima have shown a different degree of coarse, not smooth, continuous poor,limited thickening of the Echo, and some even local strong echo of plaque formation, the mean artery IMT was significantly higher（ P 〈 0.001 ）, the blood pressure was elevated（ P 〈 0.01 ）, triglyceride （TG） and total cholesterol （TC） increased （P 〈 0.001 ）.The artery intimal had improved significantly after intervention treatment compared with the pre- intervention, the IMT thickness decreased （P 〈 0.01 ）. Conclusion The children who with moderate or serious simple obesity have varying degrees of changes in the cardiovascular system. Early intervention therapy can prevent the further development of lesions.
出处
《中国实验诊断学》
2008年第9期1124-1126,共3页
Chinese Journal of Laboratory Diagnosis
关键词
儿童
单纯性肥胖症
心血管
血脂
children
simple obesity
cardiovascular
lipid
