摘要
目的:研究麦芽对雄性小鼠性激素水平的影响。方法:给予青壮年雄性小鼠灌胃麦芽煎剂,每次1mL(相当于生药0.5g.mL-1),每日2次,连续14d,观察血中促性腺激素(FSH)、黄体生成素(LH)、睾酮(T)和雌二醇(E2)的变化情况。结果:与对照组比较,治疗组小鼠血中E2水平显著增高,T水平显著下降,FSH、LH无显著变化。结论:麦芽可能通过影响雄性小鼠性腺轴而影响其性激素水平。
OBJECTIVE： To study the effect of Hordeurn vulgate on hormone level in male mice. METHODS： Male mature mice （5-6 months） were treated with Hordeum vulgare decoction 1 mL（equivalent to 0.5 g · mL^- 1 crude drug） bid for 14 consecutive days. Follicle-stimulating hormone（FSH）, luteinizing hormone（LH）, estradiol （E2） and testosterone （T） in blood were monitored. RESULTS： In Hordeum vulgate group compared normal control, serum E2 increased significantly, serum level of testosterone decreased significantly, while FSH and LH levels remained stable. CONCLUSION： Hordeurn vulgate can influence the hormone level in male mice by influencing the gonad axis of the mice.
出处
《中国药房》
CAS
CSCD
北大核心
2008年第27期2087-2088,共2页
China Pharmacy
基金
重庆市卫生局中医药科研项目(2003-B-59)
关键词
麦芽
雄性小鼠
性激素
Hordeum vulgare
Male mice
Sex hormone
