期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

血管紧张素Ⅱ受体阻断药治疗马方综合征 被引量：1

下载PDF
导出
摘要 提要:马方综合征(Marfan syndrome)是一个系统紊乱性的结缔组织病并伴有常染色体显性遗传,累及眼、骨骼、肌肉和心血管系统,表现为主动脉根部扩张、主动脉夹层和黏液瘤所致的二尖瓣改变,治疗马方综合征为主动脉根部扩张法;马方综合征患者主要的临床心血管终点事件为主动脉根部外科手术,主动脉夹层的形成和死亡。血管紧张素受体阻断药(angiotensin receptor blocker,ARB)氯沙坦能否治疗上述症状,正在研究中。
作者 陈展望 吴平生
机构地区 三亚市人民医院内科 南方医科大学南方医院心内科
出处 《岭南心血管病杂志》 2008年第4期299-301,共3页 South China Journal of Cardiovascular Diseases
关键词 马方综合征 血管紧张素Ⅱ受体阻断药 治疗
分类号 R541.1 [医药卫生—心血管疾病]
  • 相关文献

参考文献19

  • 1JUDGE D P, DIETZ H C. Marian's syndrome[J]. Lancet, 2005, 366 (9501) : 1965-1976.
  • 2刘威.氯沙坦有望用于马凡氏综合征患者主动脉瘤的预防[J].中华医学杂志,2006,86(24):1670-1670. 被引量：1
  • 3VISCONTI R P, BARTH J L, KEELEY F W, et al. Codistribution analysis of elastin and related fibrillar proteins in early vertebrate development[J]. Matrix Biol, 2003, 22(2) : 109-121.
  • 4初歌今,张清炯,郭向明.马凡综合征的临床诊断与分子生物学研究进展[J].中国实用眼科杂志,2002,20(4):245-249. 被引量：14
  • 5ISOGAI Z, ONO R N, USHIRO S, et al. Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibrilassociated protein [J ]. J Biol Chem, 2003, 278 (4) : 2750-2757.
  • 6NEPTUNE E R, FRISCHMEYER P A, ARKING D E, et al. Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome[J]. Nat Genet, 2003, 33 (3): 407-411.
  • 7LOEYS B L, CHEN I, NEPTUNE E R, et al. A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBRI or TGFBR2[J]. Nat Genet, 2005, 37 (3): 275-281.
  • 8NG C M, CHENG A, MYERS L A, et al. TGF-beta- dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome [J]. J Clin Invest, 2004,114 (11): 1596-1592.
  • 9HABASHI J P, JUDGE D P, HOLM T M, et al. Losartan, an ATI antagonist, prevents aortic aneurysm in a mouse model of Marian syndrome[J]. Science, 2006, 312 (5770): 117-121.
  • 10TIERNEY E S, FEINGOLD B, PRINTZ B F, et al. Betablocker therapy does not alter the rate of aortic root dilation in pediatric patients with Marfan syndrome[J]. J Pediatr, 2007, 150 (1): 77-82.

二级参考文献84

  • 1AoyamaT, etal. Hum Mol Genet 1993 2:2135-2140
  • 2AoyamaT, et al. J Clin Invest 1994 94:130-137
  • 3AoyamaT, etal. AmJMedGenet 1995 58:169-176
  • 4Austin MG, et al. Arch Pathol 1957 64:205-209
  • 5AlcomDm, etal. AmJHumGenet 1989 45:38
  • 6Achard C, et al. Bull Mem Soc Med Hop Paris 1902 19: 834-840
  • 7BiermannCW, etal. ScandJ UrolNephrol 1994 28 (3): 295-296
  • 8BurianHM. MMed 1958 55:1088-1090
  • 9Burian HM, et al. Arch Ophthalrmol 1960 64:671-680
  • 10Boileau-C, et al. Arch-Mal-Coeur-Vaiss 1997 90.. 1707-1712

共引文献13

同被引文献17

  • 1RAMIREZA F, DIETZ H C. Marfan syndrome: from molecular pathogenesis to clinical treatment [J]. Curr Opin Genet Dev, 2007, 17(3) : 252-258.
  • 2CANADAS V, VILACOSTA I, BRUNA I. Marfan syndrome. Part 1: pathophysiology and diagnosis [J]. Nat Rev Cardiol, 2010, 7(5): 256-265.
  • 3CANADAS V, VILACOSTA I, BRUNA I. Marfan syndrome. Part 2: treatment and management of patients [J]. Nat Rev Cardiol, 2010, 7(5): 266-276.
  • 4DE BACKER J F, DEVOS D, SEGERS P, et al. Primary impairment of left ventricular function in Marfan syndrome [J ]. Int J Cardiol, 2006, 112(3): 353-358.
  • 5KIOTSEKOGLOU A, BAJPAI A, BIJNENS B H, et al. Early impairment of left ventrieular long-axis systolic function demonstrated by reduced atrioventrieular plane displacement in patients with Marfan syndrome[J]. Eur J of Echocardiogr, 2008, 9(5) : 605-613.
  • 6DEBACKER J. The expanding cardiovascular phenotype of Marfan syndrome [J]. Eur J of Echocardiogr, 2009, 10(2): 213-215.
  • 7DE PAEPE A, DEVEREUX R B, DIETZ H C, et al. Revised diagnostic criteria for the Marfan syndrome [J. Am J Med Genet, 1996, 62(4): 417-426.
  • 8LANG R M, BIERIG M, DEVEREUX R B, et al. Recommendations for chamber quantification [ J ]. J Am Soc Echocardiogr, 2005, 18(12): 1440-1463.
  • 9RUDSKI L G,LAI W W,AFILALO J,et al. Guidelines for the echocardiographic assessment of the right heart in adults: A report from the American Society of Echocardiography endorsed by the European Association of Echocardiography,a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography [J]. J Am Soc Echocardiogr, 2010, 23(7) :685-713.
  • 10KIOTSEKOGLOU A, SUTHERLAND G R, MOGGRIDGE JC, et al. Impaired right ventricular systolic function demonstrated by reduced atrioventricular plane displacement in adults with Marfan syndrome[J]. Eur J of Echocardiogr, 2009, 10(2) : 295-302.

引证文献1

岭南心血管病杂志
2008年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部