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不同四种方案治疗骨髓增生异常综合征临床研究 被引量:2

The study of erythopietin receptor and researched 4 different plans for curing MDS
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摘要 目的研究不同四种方案治疗骨髓增生异常综合征(MDS)疗效,寻求有效的治疗的策略。方法经FAB标准确诊的MDS患者39例在积极支持治疗下,按个体差异采取不同的化疗方案进行诱导化疗。结果小剂量阿糖胞苷(LD-Ara-C)组治疗10例,完全缓解(CR)率13.5%;MA组治疗8例,CR率45.0%;DA组治疗6例,CR率40.5%;CAG组治疗15例,CR率60.5%,PR者经2个疗程治疗后,余改用其它方案治疗。结论CAG方案治疗MDS,CR率高。不良反应小,为MDS患者延长生存期,改善生活质量,提供一种可行的方案。 Objective To study the researched 4 different plans for curing MDS, and looking for the strategy which one effectivly and curly .Methods By way of FAB to diagnose standardly,39 MDS patients were cured actively.They were adopted the different plans for individual difference to carry on abduction. Results Min-dose LD-Ara-C group cured 10 examples, all relieve CR pereentage 13.5% ; MA group cured 8 examples, CR percentage 45.0% ;DA group cured 6 examples, CR percentage 40.5 % ;CAG group cured 15 exampies, CR percentage 60.5 % ; PR after two course of treatment, eured by another plans. Conclusion CAG plans cured MDS, CR percentage high. Toxin side effect small, prolonged growth times for MDS patients, change the living quality, offered one plan which one was practically.
出处 《四川医学》 CAS 2008年第9期1126-1128,共3页 Sichuan Medical Journal
关键词 骨髓增生异常综合征 小剂量阿糖胞苷 米托蒽醌 柔红酶素 myelodysplashcsyndmme ld-Arabinoside Mitoxantrone, Arabinoside Daunorubicin, Arabinoside Arabiuoside, Aclarubicin, G-CSF
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  • 1Stone R M. The difllcult problem of aeutemydoid leukemia in the older adult[J]. CA Cancer J Clin,2002,52(6) :363 - 371
  • 2Akashi K, Eto T, Shibuva T, et al. Aclarubicin induces differentiation of Leukemic progenitors in myclodysplastic symdrome cooperating with granulocyte colony-stimulating factor[ J]. leukres, 2000,24( 3 ) : 243 - 248
  • 3Vardiman J W, Harris N L, brunning R D. The world Health organization (WHO) classification of the myeloid neoplms[ J]. Blood, 2002, 100(7 ) : 2292 - 2302
  • 4Saito K, Nakamura T, Aoyagi M, et al. Lowdose cytarabine and aclarubicin in combination with granulcyte colong-stimulating factor(CAG regimen)for previously treated patients with relapsed or primary resistant acute myelogenous Leukemia (AML)and previosly untreated elederly patients with AML,seconday AML,and refractory anemia with excess blasts in transformation[J] .Int J Hematol,2000,71(3) :238 - 244
  • 5Li JM, Shen Y, Wu DP, et al. Aclarubicin and low-dose cytosine arabinoside in combination with granulocyte colony-stimulating factor in treaying acute myeloid leukemia patients with relapsed or refractory disease and myelodys plastic syndrome; a multicenter study of 112 chinese patiens[J]. Int J Hematol,2005,82(1) :48 - 54

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