摘要
目的:探讨早期中心静脉血氧饱和度在严重脓毒血症和感染性休克中的意义。方法:83例危重监护病房严重脓毒血症或感染性休克患者分为两组,生存组57例和死亡组26例,测定液体复苏前后中心静脉血氧饱和度(ScvO2),中心静脉压(CVP)、平均动脉压(MAP)和血乳酸水平,并统计导向液体复苏6小时ScvO2、CVP、MAP达标例数。结果:存活组复苏前ScvO2高于死亡组(73.18±5.61)%对(61.43±4.92)%(P<0.05),存活组6小时液体复苏ScvO2达标率高为73.68%,死亡组为23.08%,差异有显著性(P<0.01),生存组乳酸清除率(31.13±11.90)%,高于死亡组(11.17±9.51)%(P<0.01),生存组与死亡组比较液体复苏6小时CVP达标率94.74%对88.46%(P>0.05),MAP达标率92.98%对84.62%(P>0.05),均无显著差异。结论:危重监护病房严重脓毒血症和感染性休克患者ScvO2水平和病情严重程度呈正相关,早期监测对指导液体复苏治疗和判断预后有重要意义。
Objective：To study the significance of early central venous blood oxygen saturation in patients with severe sepsis and septic shock.Methods ：A total of 83 cases with severe sepsis and septic shock in intension care unit were divided into survival group（n= 57）and death group （n=26）,the central venous blood oxygen saturation （ScvO2）, central venous pressure （CVP）,mean arterial pressure （MAP）and lactic acid were measured before and after early goal-directed therapy, then added up the success rate of fluid resuscitation about ScvO,,CVP and MAP.Results：Survivors and nonsurvivors had an early SoyO2 of 73.18±5.61% VS 61.43±4.92%（P〈0.05）,had a success rate of fluid resuscitation of 73.68% VS 23.08%（P〈0.01） and had a lactate clearance of 31.13±11.90% VS 11.17±9.51%（P〈 0.01）, but they had a success rate of CVP of 94.74% VS 88.46%（P〉0.05）and had a success rate of MAP of 92.98% VS 84.62%（P〉 0.05）.Conclusion：The early levels of ScvO2 of patients with severe sepsis and septic shock in intension care unit were positively correlation with serious degree of illness and played important role in early goal-directed therapy and estimation of prognosis of illness.
出处
《现代医药卫生》
2008年第20期3025-3026,共2页
Journal of Modern Medicine & Health
关键词
中心静脉血氧饱和度
脓毒血症
感染性休克
Central venous blood oxygen saturation
Severe sepsis
Septic shock
