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香豆素衍生物的合成及结构表征 被引量:4

Synthesis and Structure Characterization of Coumarin Derivatives
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摘要 合成了11个香豆素衍生物,产率53%—79%,利用元素分析、MS和1HNMR对其结构进行了表征.同时,由2-氨基苯并噻唑(ABT)和8-甲氧基香豆素-3-甲酸乙酯(MCC)合成了给体-受体加合物ABT-MCC,通过X射线单晶衍射法测定了其晶体结构,晶体属三斜晶系,P空间群,晶胞参数为:a=9.5978(19),b=10.686(2),c=10.693(2),α=71.30(3)°,β=70.43(3)°,γ=88.99(3)°,V=973.9(3)3,Z=2,Dx=1.359 mg/m3,μ=0.200 mm-1,F(000)=416,R=0.0463,wR=0.0992.结果表明,在ABT-MCC晶体中,分子间通过N—H…N和N—H…O氢键作用形成对称的A…D…D′…A′氢键四聚体,并通过弱的C—H…O氢键连接成为一维超分子链状结构,进而分子间通过π-π堆积作用形成层状结构. Eleven new coumarin derivatives were prepared in 53 % to 79 % yields. The structures of the title compounds were characterized by elemental analysis, 1HNMR and MS. The crystal struc- ture of donor-acceptor complex ABT-MCC derived from 2-amino-1, 3-benzothiazole (ABT) and ethyl 8-mthoxycoumarin-3-carboxylate (MCC) was determined by X-ray diffraction analysis. The crystal of ABT-MCC belongs to the triclinie system, space group P1, cell parameters: a=9.5978(19),b=10.686(2),c=10.693(2),α=71.30(3)°,β=70.43(3)°,γ=88.99(3)°,V=973.9(3)3,Z=2,Dx=1.359 mg/m^3,μ=0.200 mm-1,F(000)=416,R=0.0463,wR=0.0992. X-ray diffraction reveals that the complex shows the A…D…D'…A' H-bonded tetramer. The molecules are connected via intermolecular hydrogen bonds into a one-dimensional chain structure, and are further assembled to form a layer structure via the π-π stacking.
出处 《影像科学与光化学》 CAS CSCD 2008年第5期393-402,共10页 Imaging Science and Photochemistry
基金 泰山学院科研基金资助项目(Y04-2-02)
关键词 香豆素衍生物 2-氨基苯并噻唑 给体-受体加合物 晶体结构 coumarin derivatives 2-aminobenzothiazole donor-acceptor complex synthesis crystal structure
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