摘要
目的观察电针曲池穴对高血压模型大鼠血压及血管紧张素Ⅱ(AngⅡ)含量的影响,以对其降压机理作初步探讨。方法建立高血压大鼠模型,随机分为模型组、电针组,另设正常组。经过8周治疗后,测量血压,并测定血浆及主动脉AngⅡ含量。结果模型组血压明显高于正常组,治疗后电针组血压明显降低,与模型组比较有非常显著性差异(P<0.01);模型组血浆及主动脉AngⅡ含量明显高于正常组,治疗后电针组血浆及主动脉AngⅡ含量尚未恢复到正常组水平,但明显低于模型组(P<0.01)。结论电针曲池穴可抑制两肾一夹高血压大鼠血压的升高,其降压机制可能与其综合抑制肾素-血管紧张素系统(RAS)有关。
Objective： The effect of electro- acupuncturing Quchi Point on blood pressure and angiotensin Ⅱ of 2K1C - Renal hypertensive rats was observed, so as to investigate the mechanism of lowering the blood pressure initially. Method： 2K1C - RHR model was set up, which were divided into two groups at random ： electro - acupuncture （EA） group and control group. Normal group was set in addition. After 8 - week treatment, measure the blood pressure and identify the content of plasma and Angiotensin Ⅱ in aorta. Results： The blood pressure of model group is higher than normal group, the blood pressure of EA group was cut down after treatment with a significant difference between EA and control group （P 〈 0.01 ）. The plasma concentration of Angiotensin Ⅱ in circulate and aorta is higher than normal group , and there is a significant difference between EA and control groups after treatment, although EA group is still higher than the normal group. Conclusion： Electro - acupuncturing Quchi Point could restrain the ascending blood pressure, the mechanism of lowering the blood pressure may duo to restrain the RAS in circulation and blood vessel synthetically.
出处
《湖北中医学院学报》
2008年第3期5-7,共3页
Journal of Hubei College of Traditional Chinese Medicine
基金
国家973课题<穴位效应规律的研究>
关键词
高血压
电针
曲池穴
血管紧张素Ⅱ
大鼠
Quchi Point
electro -acupuncture
Hypertension Angiotensin Ⅱ
rats
