摘要
目的分析2型糖尿病住院患者各种糖尿病慢性并发症包括大血管病变、微血管病变及神经病变的罹患情况及相应的危险因素。方法以966例2型糖尿病住院患者为研究对象,依据患者病历资料,针对各种糖尿病慢性并发症的患病情况及相应危险因素进行统计分析。结果入选患者中,合并糖尿病视网膜病变的261例,占26.9%;合并糖尿病肾脏病变的336例,占34.8%;合并糖尿病下肢血管病变的564例,占58.4%;合并糖尿病神经病变的647例,占67.0%;高血压473例,占49.0%;冠心病58例,占6.0%;脑血管病变107例,占11.1%。经多因素Logistic逐步回归分析发现,患者的年龄、病程、性别、高血压、体重指数、血糖、C肽、血清总胆固醇、尿酸、24 h尿白蛋白为各糖尿病慢性并发症的独立危险因素。结论为改善患者的预后,重视对糖尿病高危人群的早期防治,对已出现2型糖尿病的患者应采取减肥、降糖、降压、、调脂等多种措施并进行综合治疗。
Objective To analyze the morbidity rate and relevant risk factors of various chronic complications including macrovascular and microvascular complications and neuropathy. Methods 966 in-patients with type 2 diabetes mellitus were collected, the morbidity rate of various chronic complications and relevant risk factors were evaluated according to clinical materials. Results The morbidity rate of various chronic diabetic complications were listed as follows： diabetic retinopathy 26.9% （261 cases） , diatetic nephropathy 34.8% （ 336 cases） , diabetic neuropatby 67.3% （647 cases） , hypertension 49% （473 cases）, coronary heart disease （CHD） 6.0% （ 58 cases）, cerebral vascular disease （CVD） 11.1% （107 cases）, vessel complication of lower limbs 58.4% （564 cases）. Multivariate logistic regression analysis showed that age, duration of diabetes, sex, hypertension, BMI （body mass index）, plasma glucose, C-peptide total cholesterol, triglyceride, uric acid and 24 h-UAE（urinary albumin excretion） were the independent risk factors relative to various diabetic chronic complications. Conclusion In order to improve patients＇ outcome, multiple metabolic controls and synthetic treatment including reducing weight, decreasing glycemia, reducing blood pressure and regulating lipid level, etc are urgently needed in patients with type 2 diabetes mellitus.
出处
《杭州师范学院学报（医学版）》
2008年第4期243-245,253,共4页
Journal of Hangzhou Teachers College :Medical Edition
关键词
2型糖尿病
糖尿病慢性并发症
危险因素
Type 2 diabetes diabetes mellitus
chronic diabetic complication
risk factors
