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普马拉类病毒分子流行病学研究进展 被引量:3

Study on molecular epidemiology of Puumala-like virus
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摘要 普马拉病毒(Puumala virus,PUUV)属于布尼亚病毒科(Bunyaviridae)的汉坦病毒属(Hantavirus,HV),1980年首次在芬兰的普马拉地区欧洲棕背屠乎(Myodes glareolus)中发现。随着分子流行病学及分子进化等学科应用于HV的研究,不仅在欧洲及俄罗斯发现8个亚型的PUUV,在日本,韩国和中国的吉林省也发现PUUV类病毒的存在。国际病毒分类委员会将最先在日本北海道棕背鼠平(M.rufocanus)上发现的HV命名为北海道病毒(HOKV),而在韩国的东北绒鼠(M.regulus)上发现的Hv命名为Muju病毒(MUJV)。与其他型HV一样,PUUV不影响宿主动物的生长繁殖,并与宿主共进化,但能引起人较轻的肾综合征出血热(HFRS)。为更深入全面地了解其遗传特征、演化规律等生物学特性,有效地预防控制PUUV及相关病毒的感染,本文综述如下。
出处 《中华流行病学杂志》 CAS CSCD 北大核心 2008年第10期1045-1048,共4页 Chinese Journal of Epidemiology
基金 国家“十五”科技攻关计划资助项目(2003BA712A0802)
关键词 普马拉类病毒 分子流行病学 临床研究 治疗方法 Puumala-like virus Molecular epidemiology
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参考文献35

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共引文献19

同被引文献38

  • 1周济华,张海林.汉坦病毒分型及致病性的研究进展[J].国际病毒学杂志,2008,15(2). 被引量:28
  • 2唐丽华,张全福,修梅红,扈光伟,沈博,杨显达,梁米芳,李德新.在我国发现普马拉病毒新亚型[J].病毒学报,2007,23(4):320-325. 被引量:7
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