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高龄和年轻冠心病患者冠状动脉介入治疗临床对比分析 被引量:6

Clinical comparison of coronary artery interventional therapy in young adult and in geriatric patients
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摘要 目的探讨高龄和年轻冠心病患者冠状动脉介入治疗效果。方法选择在我科行冠状动脉介入治疗的冠心病患者320例,根据年龄分为年轻组(146例)、高龄组(62例)和对照组(112例),分析各组患者临床特点、病变特点及介入治疗效果。结果以急性心肌梗死起病的患者在年轻组、高龄组和对照组分别占45.2%,17.7%和23.2%(P=0.000);以心绞痛起病的患者中1周内发生心肌梗死的患者分别占47.2%、14.3%和40.0%(P=0.018);非ST段抬高心肌梗死的发生率分别为1.9%、10.5%和1.9%(P=0.000);高血压患者在3组中分别占40.4%、67.7%和56.3%(P=0.001);吸烟患者分别占71.2%、22.6%和55.4%(P=0.000);肾功能不全患者分别占1.4%、16.1%和2.7%(P=0.000);住院病死率分别占0、6.5%和0.9%(P=0.003)。结论年轻患者多以急性心肌梗死起病;高龄患者病变复杂,合并多系统疾病多,严重并发症发生率偏高。 Objective To evaluate the clinical and angiographic characteristics of young adults and geriatric patients with coronary artery disease. Methods Patients who received coronary artery interventional therapy were divided into three groups according to ages: young group (n :146), geriatric group (n =62) and control group (n =112). The clinical records and angiographic images were analyzed. Results The first manifestation was acute myocardial infarction in 45.2% of young adults, 17.7% of geriatric patients and 23.2% of controls respectively. Patients who first manifested angina developed myocardial infarction in one week in 47.2%, 14.3% and 40.0% of patients (P =0.018) respectively. Incidence of the non-ST segment elevated myocardial infarction was 1.9%,10.5% and 1. 9% (P =0. 000). 40.4%,67.7% and 56.3% of the patients had hyper-tension (P = 0. 001) ; 71. 2%, 22. 6% and 55. 4% of the patients were smokers (P = 0. 000) 1.4%,16.1% and 2.7% of the patients had renal insufficiency (P =0. 000);0,6.5% and 0.9% of the patients died in hospital (P = 0. 003). Conclusions First manifestation of most young adults with coronary artery disease was acute myocardial infarction. Geriatric patients had more complicated lesions, more often had other diseases, and had more complications.
出处 《中华老年心脑血管病杂志》 CAS 北大核心 2008年第10期751-753,共3页 Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
关键词 冠状动脉疾病 心肌梗塞 年龄因素 介入治疗 coronary disease myocardial infarction age factors interventional therapy
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