摘要
目的探讨胸部CT和血清铁蛋白、癌胚抗原检测及联合应用诊断肺癌的价值。方法选择肺肿瘤患者73例，均在治疗前行胸部CT检查和检测血清铁蛋白（SF）、癌胚抗原（CEA）两种肿瘤标志物浓度。分别计算两种方法单独及联合诊断肺癌的灵敏度、特异度、诊断正确率、阳性似然比和阴性似然比，并加以比较分析。结果二法联合检测与二法单独检测相比灵敏度、诊断正确率最高，阴性似然比最低。结论胸部CT和SF、CEA检测在肺癌诊断中具有较高价值，二者联合应用诊断肺癌具有互补作用。
Objective To investigate the value of chest CT and detection of serum CEA, SF in diagnosis of pulmonary carcinoma. Methods Chest CT were performed and serum levels of CYFRA21-1 and NSE were measured with R IA in 73 patients with pulmonary nodules, the sensitivity , specificity, efficiency, positive likelihood ratio and negative likelihood ratio of two methods for diagnosis of cancer were compared. Results Combined determinations have the highest sensitivity, efficiency and the lowest negative likelihood ratio. Conclusion Both of chest CT and detection of serum CEA and SF are important methods in diagnosis of pulmonary carcinoma and they are complementary to each other.
出处
《国际医药卫生导报》
2008年第20期77-79,共3页
International Medicine and Health Guidance News
