摘要
以丙三醇和癸二酸为单体通过熔融缩聚制得了聚癸二酸丙三醇酯(PGS),并用其预聚物(p-PGS)对聚L-丙交酯(PLLA)进行共混改性。利用傅立叶变换红外光谱(FT-IR)、核磁共振氢谱(1H-NMR)及凝胶渗透色谱(GPC)法对p-PGS的结构进行表征,并研究了改性后材料的力学性能、两相相容性、亲水性能和细胞相容性。结果表明:p-PGS具有支化分子结构,分散系数约为2.7;共混改性后的材料弹性模量和拉伸强度均有所下降,而断裂伸长率从7%显著提高到150%左右;PLLA/PGS属于海岛式共混结构,PGS以小于10μm的尺寸均匀分布在PLLA基体中;共混后材料的亲水性也有一定的提高,且几乎保持了PLLA原有的细胞相容性。
Poly（glycerol-sebacate） （PGS） was prepared from glycerol and sebacic acid by melt polycondensation, and the prepolymer （p-PGS） was blended with poly（L-lactide） （PLLA） for modification. p-PGS was studied by FT-IR, ^1H-NMR and GPC, and the mechanical property, phase compatibility, hydrophilicity and cell compatibility of the blending materials were studied. Results shows that p-PGS was branched, the polydispersity index was about 2.7, the modulus and the tensile strength of the materials decreased after modification, the break elongation increased dramatically from 7% to about 150%. PLLA/ PGS blend had sea-island structure, and PGS was equidistributed in PLLA phase with the dimension smaller than 10 μm the blends also increased hydrophilicity and kept its original cell compatibility.
出处
《功能高分子学报》
CAS
CSCD
北大核心
2008年第3期343-347,共5页
Journal of Functional Polymers
