摘要
目的观察康莱特联合沙培林治疗老年恶性胸腔积液的近期疗效、生活质量提高情况。方法56例诊断为肺癌恶性胸腔积液的老年患者随机分组,治疗组28例应用康莱特的同时给予沙培林胸腔灌注治疗,对照组28例仅用沙培林胸腔灌注治疗,4周后观察疗效。结果有效率(CR+PR)治疗组为89.3%,对照组为85.7%,治疗组疾病控制率高于对照组,但差异无统计学意义,而治疗组较对照组的生活质量明显提高,差异有统计学意义(P<0.05)。结论康莱特联合沙培林可提高恶性胸腔积液的疗效、改善患者生活质量。
Objective To evaluate the therapeutic effects and the quality of life of Kanglaite combined with Sapylin in the treatment of malig- nant pleural effusion induced by lung cancer of the elderly. Methods 56 elderly patients diagnosed as malignant pleural effusion induced by lung cancer were randomly divided into two groups. The observation group received Kanglaite combined with intrapleural injection of Sapylin, the contrast group was given injection of Sapylin alone. The therapeutic effect was observed after four weeks. Results The effective rate of observation group（89.3% ） was more than that of the contrast group（ 85.7% ）. While there was no significant difference in the combined group （P 〉 0.05）. But observation group at increasing body was superior to those in contrast group and there was significant difference（P 〈 0.05 ）. Conclusion Kanglaite combined with Sapylin can impove efficacy and the quality of life in the treatment of malignant pleural effusion.
出处
《肿瘤基础与临床》
2008年第5期413-414,共2页
journal of basic and clinical oncology
关键词
康莱特
沙培林
恶性胸腔积液
生活质量
Kanglaite
Sapylin
malignant pleural effusion
quality of live
