期刊文献+

扶正活血法为主治疗糖尿病足坏疽112例 被引量:23

Therapy mainly for strengthening healthy energy to promote blood circulation in treating 112 diabetic patients with gangrene
下载PDF
导出
摘要 目的:评价扶正活血法为主的治疗方法对糖尿病足坏疽的临床疗效。方法:观察112例糖尿病足坏疽患者的创面愈合情况、常见中医证候量化积分及生命质量,评价扶正活血法为主的治疗方法对糖尿病足坏疽的临床疗效。结果:112例患者治愈58例,显效12例,好转36例,无效6例,愈显率62.5%(70/112),截肢率8.9%(10/112)。将104例糖尿病足坏疽三期患者依据坏疽分级分为Ⅰ级、Ⅱ级和Ⅲ级,其愈显率分别为83.3%(30/36)、55.6%(35/63)和20%(1/5),截肢率分别为0%、12.7%(8/63)、40%(2/5)。治疗后患者大部分临床症状与坏疽数量、深浅、范围,溃疡表面色泽,新生肉芽组织,新生上皮组织等较治疗前均明显改善(P<0.05)。患者治疗后生命质量总分较治疗前明显改善(P<0.01),尤其表现在糖尿病对患者生理、心理以及治疗对患者影响等方面(P<0.05)。结论:扶正活血法为主能有效治疗糖尿病足坏疽。 Objective: To evaluate the effects of the therapy mainly for strengthening healthy energy to promote blood circulation in treating diabetic patients with gangrene.Methods: A series of 112 diabetic patients with gangrene were investigated before and after treatment in the changes of wounds,clinical symptoms and quality of life.Results: Fifty-eight cases were cured,12 cases showed response,36 cases improved,and 6 cases failure of treatment.The total obvious effect rate was 62.5%(70/112) and the amputation rate was 8.9%(10/112).The 104 diabetic cases of three-stage gangrene were classified into gradeⅠ,Ⅱ and Ⅲ.The total effect rates of the diabetic cases of gradeⅠ,Ⅱ and Ⅲ were 83.3%(30/36),55.6%(35/63) and 20%(1/5),and the amputation rates were 0%,12.7%(8/63),and 40%(2/5) respectively.After the treatment,the clinical symptoms,gangrene number,gangrene area and gangrene depth were obviously improved(P〈0.05),and the quality of life was obviously improved(P〈0.01),especially in physical condition,emotional well-being and therapeutic effects on patients(P〈0.05).Conclusion: Strengthening healthy energy to promote blood circulation is effective in treating diabetic patients with gangrene.
出处 《中西医结合学报》 CAS 2008年第10期1005-1009,共5页 Journal of Chinese Integrative Medicine
基金 上海市重点学科建设资助项目(No.T0304)
关键词 扶正 活血 糖尿病足 坏疽 临床研究 strengthening body resistance, activating blood, diabetic foot, gangrene, clinical research
  • 相关文献

参考文献7

二级参考文献26

  • 1吕仁和,张洁荣,高彦彬.消渴病(糖尿病)中医分期辨证与疗效评定标准[J].中国医药学报,1993,8(3):54-56. 被引量:451
  • 2糖尿病足(肢端坏疽)检查方法及诊断标准(草案)[J].中国糖尿病杂志,1996,4(2):126-126. 被引量:593
  • 3朱元颖,阙华发.缺氧诱导因子1与祛瘀生新[J].中西医结合学报,2006,4(1):94-97. 被引量:8
  • 4邓兆智,何羿婷,余煜棉.计算机模式识别法对类风湿性关节炎中医证候判断与常规临床判断的比较[J].中国中西医结合杂志,1996,16(12):727-729. 被引量:15
  • 5王阶 陈可冀 史载祥主编.血瘀证诊断标准及定量诊断[A].陈可冀,史载祥主编.实用血瘀证学[C].北京:人民卫生出版社,1999.22~23.
  • 6青春,林炜栋,刘琰,等.糖尿病合并创面难愈等并发症形成机制的研究.//陆树良.烧伤创面愈合机制与新技术.北京:人民军医出版社.2003:135-154.
  • 7Pugh CW,Ratcliffe PJ.Regulation of angiogenesis by hypoxia:role of the HIF system.Nat Med.2003, 9(6):677-684.
  • 8Marti HJ,Bernaudin M,Bellail A,et al.Hypoxiainduced vascular endothelial growth factor expression precedes neovascularization after cerebral ischemia.Am J Pathol.2000, 156(3):965-976.
  • 9Cramer T,Schipani E,Johnson RS,et al.Expression of VEGF isoforms by epiphyseal chondrocytes during low-oxygen tension is HIF-1 alpha dependent.Osteoarthritis Cartilage.2004, 12(6):433-439.
  • 10Abraham D,Krenn K,Seebacher G,et al.Upregulated hypoxia-inducible factor-1 DNA binding activity to the vascular endothelial growth factor-A promoter mediates increased vascular permeability in donor lung grafts.Ann Thorac Surg.2004, 77(5):1751-1755.

共引文献898

同被引文献272

引证文献23

二级引证文献174

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部