摘要
目的了解上海浦东新区部分社区人群中慢性肾脏病(CKD)的患病率以及CKD的危险因素。方法在浦东新区梅园街道,随机抽取20岁以上成年人共520名,填写调查问卷表并进行体格检查和实验室检查测得尿白蛋白/肌酐比值、尿常规和血肌酐、葡萄糖、血脂。以简化MDRD公式计算估计肾小球滤过率(eGFR)。应用SPSS11.5统计分析软件进行统计学分析。结果504名居民资料完整,经年龄性别标化后白蛋白尿的患病率是6.76%,血尿的患病率为2.82%,eGFR<60 mL/min的患病率为1.25%。按K/DOQI诊断标准,CKD的患病率为8.94%,CKD的知晓率为36.14%。Logistic回归分析显示,高血压、糖尿病、年龄是白蛋白尿的独立危险因素,年龄、高血压、糖尿病是CKD的危险因素。结论上海浦东梅园社区人群CKD的患病率8.94%,CKD的知晓率为36.14%。CKD的危险因素包括高血压、高血糖、高三酰甘油血症、年龄等。
Objective To investigate the prevalence of chronic kidney disease and risk factors. Methods Five hundred and twenty residents from eight communities of Meiyuan district in Shanghai Pudong were randomly selected using a stratified, multistage sampling. All residents were interviwed and tested for morning spot urine of albumin to creatinine ratio （ACR） （abnormal： ≥30 mg/g） ;morning spot urine dipstick of hematuria confirmed by urine microscopy（ abnormal： 〉 3 red blood cells/Hp） ;reduced renal function-estimated glomerular filtration rate by abbreviated MDRD equation estimater GFR[ abnormal： 〈 60 mL/（ min · 1.73 m^2） ]. The associations of kidney damage indicator with age, gender, hypertension, diabets mellitus, smoking, income, education, cholesterol, triglyceride and smoking were detected by questionnair and physical examination. Results Eligible data of 504 subjects were collected in the study. The prevalence of albuminuria was 6. 76% （95% CI：4. 21% -9. 31% ） ;after the adjustment of age and gender component,the prevalence of hematuria was 2. 82% （95% CI：I. 51% -4. 13% ） ,of the reduced renal function,1.25% （95% CI：0.29% - 2.21% ）. Approxomately 8.94% subjects had at least one indicator of kidney damage. Age, hypertension and diabets meUitus were independently associated with CKD. Conclusion The prevalence of chronic kidney disease in Shanghai Pudong Meiyuan district is 8.94% and the recognition is 36. 14%. Independent risk factors associated with chronic kidney disease are age, hypertention and diabets mellitus.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2008年第11期961-963,共3页
Chinese Journal of Practical Internal Medicine
关键词
慢性肾脏病
患病率
危险因素
chronic kidney disease
prevalence
risk factor
