摘要
目的研究胃癌患者血浆D-二聚体（D—dimer）和纤维蛋白原（Fg）水平变化与胃癌疗效、预后的关系，探讨其对胃癌诊治的临床意义。方法取300例胃癌患者和40例对照组（健康体检者）的静脉血，血浆D—dimer含量采用乳胶凝集半定量法测定，血浆Fg含量采用Clauss法测定。结果300例胃癌患者中，胃癌初治组、难治转移组、治疗缓解组的血浆D—dimer和取水平明显升高，与对照组比较差异有统计学意义；治疗缓解组的血浆D—dimer、Fg水平较初治组及难治转移组有明显下降。结论血浆D—dimer和Fg水平变化与胃癌的病情变化及预后有明显相关性，可作为胃癌的诊断、治疗和预后判断的一项早期实验室参考指标。
Objective To investigate correlation of plasma level of D - dimer and fibrinogen with therapeutic effect and prognosis of gastric cancer, and its diagnostic and therapeutic significance. Methods The present study included 300 patients suffering from gastric cancer and 40 normal adults. Results The D - dimer and fibrinogen levels were increased in the primary therapy group, metastasis group and relief group compared to that in the normal adult group. The D - dimer and fibrinogen levels were decreased in the relief grnup compared to that in primary therapy group and the metastasis group. Conclusion Plasma D - dimer and fibrinogen is closely related with the progression of gastric cancer patients, condition and prognosis.
出处
《中国实用医刊》
2008年第20期22-23,共2页
Chinese Journal of Practical Medicine
