摘要
目的分析变应性血管炎(AV)的病因、临床表现、实验室检查、治疗及预后方面的特点,以进一步提高对该病的认识。方法回顾性分析中山大学附属第二医院1991-2007年临床及病理确诊为AV的住院患者的病因、临床表现、实验室检查、治疗及预后。结果41例患者中男17例,女24例,平均发病年龄(40.59±15.78)岁,以多形性皮肤损害为主要表现,双下肢伸侧受累为主,关节受累、胃肠道受累及肾脏受累的发生率分别为21.9%、9.7%及12.1%,经激素和/或免疫抑制剂治疗后随访发现有82.8%的患者获得完全缓解。结论AV多见于成年人,以多形性皮疹为主要表现,系统性损害少见,预后好。
Objective To further study the etiology,clinical manifestation,experimental examination,treatment and prognosis of Allergic Vasculitis（AV）.Methods Retrospective study of 41 patients with biopsy-proven cutaneous leukocytoclastic vasculitis diagnosis as having AV,who were seen at our hospital from 1991 to 2007.Results Women outnumbered men and the mean onset of AV was（40.59±15.78）yearsold,The skin lesions were polymorphous and were predominantly located in the lower extremities,particularly on the extensor aspect of the leg.The incidence rate of joint,gastrointestinal and renal complications were 21.9%,9.7%and 12.1%,respectively.After corticosteroids and/or immunosuppressive agent treatment and in the follow-up,82.8%of patients had complete recovery.Conclusion AV is frequent in adults and generally a benign disease confined exclusively to the skin,the visceral involvement is scarce and its prognosis is excellent.
出处
《中国实用医药》
2008年第28期5-6,共2页
China Practical Medicine
