摘要
目的了解强迫症（OCD）持续性注意功能损害情况及其相关因素。方法对65例OCD患者在入组时进行连续操作试验（CPT）测试，以65例正常健康人进行对照，采用耶鲁-布朗强迫量表（Y—BOCS）、汉密尔顿焦虑量表（HAMA）、汉密尔顿抑郁量表（HAMD）评定病情与情绪，并对测试结果与病程、年龄、病情严重度和焦虑、抑郁情绪等进行回归分析。结果OCD患者CPT视觉单目标持续性注意测验（VOT）、视觉连续目标持续性注意测验（VST）、听觉持续性注意测验（ET）均高于正常对照组（z=3．79～8．62，P〈0．05），CPT评分与病程、年龄无关（标准化回归系数Beta=0．012—0．198，P〉0．05），与病情严重度和情绪有相关性（VOTCV Beta=0．566，VOTHAMA Beta=0．382，VOTHAMD Beta0．294，P〈0．05）。结论OCD患者存在一定的注意损害，注意损害与病情严重度和情绪有关。
Objective： To explore the condition and the relative factors of the attention function damage in patients with obsessive - compulsive disorder （OCD）. Methods ： Sixty - five OCD cases were tested with the continuous performance tests （CPTs） as well as Yale - Brown Obsessive - Compulsive Scale （ Y - BOCS）, Hamilton Anxiety Rating Scale（ HAMA）, Hamilton Depression Rating Scale （HAMD） and compared with 65 normal people. Regression analysis was then carried out with course, severity, age and emotion. Results：Most items （visual one objective continuous performance test, VOT; visual successive objective continuous performance test, VST; ear continuous performance test, ET） of the CPTs of patients were higher than that of the normal persons（z = 3.79 - 8.62 ,P 〈 0.05）, the scores had correlated with the condition of the illness and emotion（VOT CV Beta = 0. 566, VOT HAMA Beta =0. 382, VOT HAMD Beta 0. 294, P 〈 0.05 ）, but no relation with course and age （ Beta = 0. 012 - 0. 198, P 〉 0.05 ）. Conclusion ： The OCD patients have attention damage, which had correlation with the severity of illness and emotion.
出处
《上海精神医学》
2008年第5期268-270,共3页
Shanghai Archives of Psychiatry
关键词
强迫症
注意
连续操作试验
Obsessive- compulsive disorder Attention Continuous performance test
