摘要
目的:研究阿立哌唑对精神分裂症患者生活质量的影响。方法:用Meta分析对7项关于阿立哌唑与其他抗精神病药影响精神分裂症患者生活质量比较分析的文献进行Meta分析。结果:在躯体功能、心理功能和社会功能维度3方面,阿立哌唑治疗前与治疗后组内比较的效应依次为-1.93、-2.61、-1.96,95%可信区间(CI)依次为(-3.51,-0.34)、(-4.16,-1.07)、(-3.76,-0.15),阿立哌唑组与对照组治疗后组间比较效应依次为1.03、0.70、1.00,95%CI依次为(0.51,1.91)、(-0.14,1.53)、(-0.03,2.03)。结论:阿立哌唑改善精神分裂症患者生活质量明显,对躯体功能维度的改善优于对照药。
Objective： To study the further effect of aripiprazole on the quality of life in schizophrenics. Method： Meta-analysis was made for 7 papers about comparative studies on life quality of schizophrenics affected by aripiprazole and other antipsychotics. Results： On the aspects of physiological health, psychological health and social function,the average effects within aripiprazole group were respectively - 1.93, - 2.61, - 1.96, and 95% CI were（ - 3.51, - 0.34）, （ - 4.16, - 1.07 ）, （ - 3.76, - 0.15 ）. Average effects between aripi- prazole and other antipsychotics were respectively 1.03,0.70,1.00, and 95 % CI were （0.51,1.91 ）, （ -0.14, 1.53） ,（-0.03,2.03）. Conclusion： Aripiprazole can significantly improve the quality of life in schizophrenics and is better than control drugs on improving physiological health.
出处
《临床精神医学杂志》
2008年第5期322-323,共2页
Journal of Clinical Psychiatry
