摘要
研究鳙鱼(Aristichthysnobilis)和尼罗罗非鱼(Tilapianilotica,=Oreochromisnilotica)血液中红细胞的微核率,判断常用水产药物孔雀石绿(C6H5ClC6H4N(CH3)2l2Cl)的诱变性.对鳙鱼的孔雀石绿实验浓度分别为0.02、0.1、0.2、0.5mg/L,对尼罗罗非鱼的孔雀石绿实验浓度分别为0.2、0.5、1.0mg/L。二种鱼均设平行组和空白对照组。实验水温18~25℃,经7d的实验结果显示:在实验浓度下的孔雀石绿均能使鳙鱼和尼罗罗非鱼红细胞出现具有统计一意义的微核率,且随药物浓度的增加,微核率呈上升趋势。说明孔雀石绿的应用可能对养殖动物具有致突变作用。
The mutagenic effect of a kind of aquatic medicine used frequently - Malachite green(C6H5C[C6H4N(CH3)2]CL)-was evaluated by observing the micronuclcus ratc in red blood cells of Aristichthys nobilis and Tilapia nilotica. The malachite green concentration for Aristichthys nobilis is 0.02,0. 1 .0.2.0.5 mg/L-1. respectively. for Tilapia nilotica is0.2.0.5. 1 .0 mg L-1.respectively. Each experiment consists of two groups of equal rank and a contrast group without any medicine. The water temperature during the test is 180 to 25℃. after 7 days' experiment. the result shows that malachite green within testing conccntration can induce the red blood cells of the two kinds of fishes to be micronucleus rate in statistical sense, and the rate increases as the concentration of malachite green increases. It is believed that using the medicine has probably the mutagenic effect on cultured livillg things.
出处
《集美大学学报(自然科学版)》
CAS
北大核心
1997年第2期55-57,共3页
Journal of Jimei University:Natural Science
关键词
微核率
孔雀石绿
诱变性
鱼
水产药物
micronucleus rate. malachite green. mutagenic effect