摘要
目的:研究心功能正常的非永久性心房颤动患者转为窦性心律前后血浆脑钠肽(BNP)水平的变化,探讨血浆BNP水平在控制房颤发生中的作用。方法:测定74例心功能正常的非永久性房颤患者转律前后的血浆BNP变化,并与30例窦性心律患者作比较。结果:房颤患者在复律成功后,血浆BNP水平明显降低(均P<0.01)。40例阵发性房颤患者的血浆BNP水平由复律前(69.2±17.8)pg/mL降至(27.8±15.2)pg/mL,25例持续性房颤患者的血浆BNP水平由复律前(74.6±19.5)pg/mL降至(28.9±17.3)pg/mL。结论:血浆BNP水平可预测房颤的发生和终止。
Objective To study the changes of plasma brain natriuretic peptide （BNP） levels before and after cardioversion in non-permanent atrial fibrillation patients with normal left ventricle function. Methods The plasma BNP levels were measured in 74 non-permanent atrial fibrillation patients and 30 healthy persons with sinusrhythm. Results After successful cardioversion, the plasma BNP level was decreased significantly. After restoration to sinus rhythm, the average level of plasma BNP was dropped from （69.2 ± 17.8）pg/mL to （27.8 ±15.2）pg/mL in forty patients with paroxysmal atrial fibrillation, and the average level of plasma BNP was dropped from （74.6 ± 19.5） pg/mL to （28.9 ± 17.3）pg/mL in twenty five patients with persistent atrial fibrillation. Conclusion The plasma BNP level could be used to predict the occurrence and termination of atrial fibrillation.
出处
《实用医学杂志》
CAS
2008年第20期3492-3493,共2页
The Journal of Practical Medicine
关键词
心房颤动
利钠肽
脑
心房重构
复律
Atrial fibrillation Natriuretic peptide, brain Atrial remodeling Cardioversion
