摘要
目的观察联合应用速眠新Ⅱ和戊巴比妥钠对西藏小型猪的麻醉效果。方法采用速眠新Ⅱ（0.1mL/kg）肌内注射和3%戊巴比妥钠生理盐水溶液（0.2 mL/kg）静脉注射联合麻醉方法对15头行胚胎移植术的西藏小型猪进行麻醉,观察动物麻醉维持时间、镇痛效果、呼吸频率和心率变化及术后苏醒情况。结果80%（12头/15头）西藏小型猪初始量麻醉状态维持45 min以上,20%（3头/15头）西藏小型猪手术过程中追加麻醉。麻醉期间肌肉松弛效果好,动物呼吸和心率平稳。手术过程中西藏小型猪呼吸频率为（12-22）次/min,心率为（63-85）次/min,麻醉过程中未出现麻醉死亡,术后苏醒时间为30-60 min。结论速眠新和戊巴比妥钠混合麻醉效果好,且麻醉剂量较以往大幅减少,术后苏醒快。戊巴比妥钠联用速眠新复合麻醉对西藏小型猪是一种较理想的麻醉方法,且动物麻醉安全性高。
Objective To observe the anesthetic effect of pentobarbital sodium in combination with sumianxin Ⅱ on Tibet mini-pigs.Methods 15 Tibet mini-pigs were anesthetized for embryo transplantation using sumianxin Ⅱ（0.1 mL/kg,im） and pentobarbital sodium（0.2 mL/kg,iv）,and to observe the maintenance of anesthetic and analgesic effect,breathing frequency（BR）,heart rate（HR）,and resuscitation time after operation.Results 80% of the pigs maintained anesthetic condition for 45 min after first administration.20% of the pigs were boosted during operation.The BR and HR of pigs during operation were（12-22）/min and（63-85）/min,respectively.No pigs died of anesthesia.All pigs reanimated at 30 min～60 min after operation.Conclusions It is a good anesthesia method using pentobarbital sodium in combination with sumianxin Ⅱ,and the dose is reduced considerably.The pigs reanimate soon after operation.The muscle is well relaxed,and BR and HR are kept stable during anesthesia.It is an excellent and safe method to anesthetize Tibet mini-pigs using pentobarbital sodium in combination with sumianxin Ⅱ.
出处
《中国比较医学杂志》
CAS
2008年第10期29-31,共3页
Chinese Journal of Comparative Medicine
关键词
戊巴比妥钠
速眠新Ⅱ
西藏小型猪
麻醉
Pentobarbital Sodium
Sumianxin Ⅱ
Tibet Mini-pigs
Anesthesia
