摘要
目的:观察阿托伐他汀对青年高脂血症患者血清超敏C反应蛋白(Hs-CRP)的影响。方法:76例青年高脂血症患者(年龄18～39岁)口服阿托伐他汀(Atorvastatin)20 mg,1次/d,连续治疗8周。检测患者血清Hs-CRP和血脂水平,并进行相关性分析。结果:青年高脂血症患者血清Hs-CRP水平明显高于正常值,且与血清低密度脂蛋白胆固醇(LDL-C)水平呈正相关,治疗后血清Hs-CRP水平明显低于治疗前(P<0.05)。结论:阿托伐他汀治疗能显著降低血清Hs-CRP水平。
Objective： To observe the effect of atorvastatin on the level of serum high sensitivity C reactive protein（Hs-CRP） in young adult patients with hyperlipemia.Methods： Seventy-six young adult patients（aged 18-39 years） with hyperlipemia were treated with atorvastatin at 20 mg/d for 8 weeks.The levels of serum Hs-CRP and lipid were determined before and after the treatment.Results： The level of serum Hs-CRP was obviously higher than normal in the hyperlipemia patients and significantly decreased after 8 weeks of atorvastatin treatment（P〈 0.05）.Conclusion： In young adult patients with hyperlipemia,the level of serum Hs-CRP can be significantly decreased by atorvastatin.
出处
《医学研究生学报》
CAS
2008年第10期1047-1048,1052,共3页
Journal of Medical Postgraduates
基金
国家“十一五”科技支撑计划资助项目(批准号:2006BAI02A06)
关键词
高脂血症
超敏C反应蛋白
阿托伐他汀
Hyperlipemia
High sensitivity C reactive protein
Atorvastatin
