摘要
目的:探讨异丙嗪注射液致过敏性休克的临床特点及规律,为临床合理用药提供参考。方法:通过检索《万方数据医药信息系统》(1998-2007年)、《中国期刊全文数据库》(1979-2007年)和王永铭主编的《药物不良反应多媒体光盘》(1960-1997年)中关于异丙嗪注射液致过敏性休克的病例报告,对其进行统计分析。结果:共检索到异丙嗪注射液引起过敏性休克19例,经积极抗休克治疗后18例恢复正常,1例死亡。结论:异丙嗪注射液引起的过敏性休克应引起临床医务人员高度重视。
Objective:To investigate the clinical features and disciplines of allergic shock induced by promethazine injection and provide information for rational use of promethazine injection in clinic.Methods:The case reports of allergic shock induced by promethazine injection from literatures were collected and analyzed.Results:19 cases of allergic shock induced by promethazine injection were searched during 1960 -2007,including 18 cases recuperated by anti-shock treatment and one case died.Conclusion:Promethazine injection could induce allergic shock,which should be paid attention to by clinician.
出处
《中国药物应用与监测》
CAS
2008年第5期58-60,共3页
Chinese Journal of Drug Application and Monitoring
关键词
异丙嗪
过敏性休克
药品不良反应
Promethazine
Allergic shock
Adverse drug reaction