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抑制肾素-血管紧张素-醛固酮系统药物在延缓糖尿病肾病中的作用 被引量:12

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摘要 糖尿病患者发生糖尿病肾病(diabetic nephropathy,DN)后,肾小球滤过率(GFR)随病程线性下降(每年10—12nd,/min^-1),大多数患者于10年后进展为肾功能衰竭。DN的临床诊断依据是持续性蛋白尿(指24h尿蛋白排出量〉300mg),初次确定DN需2—3次尿蛋白检测均为阳性,大部分糖尿病病程10年以上,无其他肾脏或泌尿系统疾病的临床或实验室证据。
作者 徐成斌
出处 《中华心血管病杂志》 CAS CSCD 北大核心 2008年第10期957-959,共3页 Chinese Journal of Cardiology
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