摘要
目的调查县级医院肺炎克雷伯菌感染的耐药现状,为临床医师合理用药提供依据。方法药敏试验采用K-B法,产超广谱β-内酰胺酶(ESBLs)细菌检测采用纸片确证试验。结果肺炎克雷伯菌产ESBLs率为34.7%;216株肺炎克雷伯菌对亚胺培南和美罗培南100.0%敏感,对阿米卡星耐药率为25.0%,对其余9种常用抗菌药物耐药率均>30.0%。结论县级医院肺炎克雷伯菌的耐药性也很严重,应重视监测与控制,预防其医院感染的发生与流行。
OBJECTIVE To investigate drug-resistance status of Klebsiella pneumoniae in county hospital and provide the reference for rational application of antibiotics. METHODS Drug-resistance was analyzed by K-B methods. The ESBLs producing strains were detected by disc confirmed test. RESULTS The detection rate of ESBLs producing K. pneumoniae.was 34. 7% in our hospital. Among 216 strains of K. pneumoniae, the susceptibility rates to imipenem and meropenem were all 100.0%. And the resistant rate to amikaein was 25.0%. The resistant rates to the other 9 antibiotics were all over 30. 0%. CONCLUSIONS Drug-resistance status of K. pneumoniae is very serious in county hospital We should think highly of monitoring and controlling drugresistance of clinical strains in order to prevent breaking out and surveillance.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2008年第10期1452-1453,共2页
Chinese Journal of Nosocomiology
关键词
县级医院
肺炎克雷伯菌
医院感染
耐药性
County hospital
Klebsiella pneumoniae
Nosocomial infection
Drug-resistance
