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1433例唇腭裂患者临床资料分析 被引量:3

Analysis of 1433 cleft lip and palate cases
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摘要 目的:分析先天性唇腭裂的发病情况及特点,为唇腭裂的预防提供临床资料。方法:对1433例先天性唇腭裂患者进行回顾性临床分析。结果:本组病例中,唇裂390例,唇裂伴腭裂794例,单纯腭裂249例;男性明显多于女性(2.35:1),但在不完全性腭裂中,女性多于男性(1:0.87);在单侧唇裂伴或不伴腭裂及完全腭裂中,左侧明显多于右侧(3.58:1);有家族遗传史的病例占总病例的6.35%;母亲妊娠初期经历危险因素316例,占22.05%;85.97%的患者来自农村;唇腭裂伴发其他畸型者42例,占2.93%。结论:多基因遗传与胚胎发育早期的环境因素是唇腭裂发病的重要因素。 Objective: In order to know the clinical and deformity condition in patients with cleft lip and palate, further investigate related possible factors with cleft lip and palate,and provide clinical data for prevention to cleft lip and palate. Method: 1433 patients with cleft lip and palate were analyzed statistically. Result: In these cases, there were cleft lip 390 cases (27.22%), cleft lip with cleft palate 794 cases (55.41%), and cleft palate 249 cases (17.38%).In all cases, males were more than females (2.35: 1), but in uncomplete cleft palate, females were more than males (1:0.87).In eases of the unilateral cleft lip with or without palate and the complete cleft palate, the incidence of left side cleft was significant higher than that of the right side (3.58: 1).A familial disposition was found in 91 of the 1433 families examined (6.35%). Mother underwent danger factors in the first three months of pregnancy:316 cases were found in 1433 eases (22.05%); 85.97 % patients were from countrycide.42 cases had accompaning deformity (2.93%). Condution: .It is suggested that the cleft lip and palate formation may be related with multiple genes and environmental condition in early stage of embryo.
出处 《临床口腔医学杂志》 2008年第10期619-621,共3页 Journal of Clinical Stomatology
关键词 唇腭裂 临床资料 统计 cleft lip and palate clinical data statistic
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  • 1沈庆赋,傅豫川.2820例先天性唇腭裂统计分析[J].口腔医学纵横,1994,10(2):123-123. 被引量:7
  • 2肖坤则,张芝燕.中国唇腭裂的流行病学[J].中华医学杂志,1989,69(4):192-194. 被引量:39
  • 3陈伟良,陈光晔,任材年,张志光.1524例先天性唇腭裂的临床分类和发病因素分析[J].口腔医学纵横,1996,12(1):20-22. 被引量:21
  • 4胡诞宁.唇裂与腭裂的遗传规律研究[J].中华医学杂志,1982,62:31-31.
  • 5田奉宸 吴延椿 等.天津市先天性唇腭裂发病情况的调查报告[J].中华口腔科杂志,1981,16(4):209-209.
  • 6谷砻治 渡边一郎 田代英雄 等.唇腭裂患者的临床统计观察[J].日口盍志,1991,16:62-62.
  • 7邱蔚六.先天性唇、面裂和腭裂,口腔颌面外科学:第3版[M].北京:人民卫生出版社,1993.345.
  • 8牟利理加 森口隆彦 光屿功 等.川琦医科大学附属医院形成外科过去10年间唇腭裂手术患者的统计观察[J].日口盍志,1990,15:99-99.
  • 9王振芬 苏香花 赵风萍 等.刑台地区汉族人MN血型分布的调查[J].中国输血杂志,1998,11(1):40-40.
  • 10.发生率和分类[A].宋儒耀.唇裂与腭裂的修复[M] 第4版[C].北京:人民卫生出版社,2003.3-7.

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  • 1王旭义,李光早.1811例先天性唇腭裂患者临床资料的统计和分析[J].安徽医学,2009,30(3):281-284. 被引量:9
  • 2Mirfazeli A, Kaviany N, Hosseinpour KR, et al. Incidence of cleft lip and palate in gorgan-northern iran:an epidemiologi- cal study [ J 1. Oman ned J, 2012,27 (6) :461 - 464.
  • 3Souza J, Raskin S. Clinical and epidenfiological study of oro- facial clefts[ J]. J Pediatr (Rio J), 2013,89(2) :137 - 144.
  • 4McDonnell R, Owens M, Delany C, et al. Epidemiology ofOrofacial Clefts in the East of Ireland in the 25-year Period 1984 - 2008 [ J ]. Cleft Palate Craniofac J, 2013 [ Epub a- head of print].
  • 5Longombe AO,Tshimbila Kabangu JM. The epidemiological approach of clefts lip and palate in the eastern of Democrat- ic Republic of Congo [ J ]. Ann Chir Plast Esthet, 2012,57 (3) :245 -249.
  • 6Gonzolez-Osorio CA, Medina-Solis CE, Pontigo-Loyola AP, et al. Ecologic study in Mexico ( 2003 - 2009 ) on cleft lip and/or palate and associated sociodemographic, socioeco- nomic and pollution factors [ J ]. An Pediatr ( Bare ), 2011, 74(6) :377 -387.
  • 7Silberstein E, Silberstein T, Elhanan E, et al. Epidemiology of cleft lip and palate among Jews and Bedouins in the Ne- gev[J]. Isr Med Assoc J,2012,14(6) :378 -381.
  • 8Doray B, Badila-Timbolschi D, Schaefer E, et al. Epidemiol- ogy of orofacial clefts ( 1995 - 2006 ) in France ( Congenital Malformations of Alsace Registry)[J]. Arch Pediatr,2012, 19(10) :1 021 -1 029.
  • 9杨芒,石斌,尹超.甘肃省2245例先天性唇腭裂发病的危险因素探讨[J].兰州大学学报(医学版),2007,33(4):29-31. 被引量:6
  • 10张芳真,郑苍尚,邓永强.1320例唇腭裂患者临床统计分析[J].口腔医学研究,2008,24(1):82-84. 被引量:18

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