摘要
目的:研究了哥王95%、75%、50%乙醇提取物、水提物及95%乙醇提取物的石油醚、氯仿、乙酸乙酯、正丁醇萃取部位对肿瘤细胞的增殖抑制作用,确定了哥王抗肿瘤活性部位。方法:采用四甲基偶氮唑盐(MTT)比色法考察了哥王不同提取物及95%乙醇提取物的不同溶剂萃取部位对Hela、SGC-7901、Bel-7402细胞的抗肿瘤活性。结果:了哥王95%乙醇提物对Hela、SGC-7901细胞有良好的抗肿瘤活性,其石油醚、氯仿、乙酸乙酯萃取部位对Hela、SGC-7901细胞均有不同程度的抗肿瘤活性。结论:石油醚、氯仿、乙酸乙酯萃取部位有较强的抗肿瘤活性,初步确定为了哥王抗肿瘤活性部位。
Objective： To estimate the anti -tumor activity of different extracts and different parts of 95% ethanol extracts of Wikstroemia indica （ L. ） C. A. Mey. Methods ： MTT assay was applied to screen the anti - tumor effect of the extracts of Wikstroemia indica （L.） C. A. Mey. on 3 tumor cell lines in vitro. Results： 95% ethanol extracts had strong inhibitory effect on different tumor cell lines. The anti - tumor activity of petroleum part, chloroform part and ethyl acetate part are various in vitro. Conchtsion： Petroleum part, chloroform part and ethyl acetate part,which are considered as activity parts of Wikstroemia indica （ L. ） C. A. Mey. ,have considerable cytotoxic effect.
出处
《中华中医药学刊》
CAS
2008年第11期2520-2522,共3页
Chinese Archives of Traditional Chinese Medicine
关键词
了哥王
抗肿瘤活性
活性部位
Wikstroemia indica （ L. ） C. A. Mey.
anti - tumor activity
activity parts
