摘要
目的:探讨抗癌药局部导入并放射治疗浅表肿瘤的临床效果。方法:对伴两个浅表病灶的肿瘤患者12例,采用自身对照的方法分为两组,较大病灶给予局部导入抗癌药合并放疗(导放组),另一病灶给予单纯放疗(单放组),两组病灶均给予常规放疗(每周5次,每次2Gy),靶区剂量(D_T)60Gy/6W.30次。结果:导放组 CR 率为83%,单放组为33%,两组差异有显著性。导放组皮肤反应明显重于单放组(P<0.01),但未影响治疗,也未增加患者的全身反应。结论:抗癌药导入并放射疗法是一种治疗浅表肿瘤的有效方法之一。
Objective:In order to investigate the effect of anti-cancer drug iontophoresis combined with radiotherapy on the superficial tumors.Methods:12 patients who were suffering from two tumor lesions were studied from April,1993 to December,1994,They were divided into two groups with self- contrast method.The treatment group (12 tumor lesions) were treated with anti-cancer drug ion- tophoresis and ratiotherapy,the anothers were only treated with radiotherapy as a control group.The dose of radiotherapy was 2Gy,5 tiros per week,total 30 times in both groups.Results:The CR rate of treatment group was 83%(10/12 cases);the CR rate of control group was 33% (4/12 cases)There was a significant difference (P<0.01),The skin adverse responses (blister,epidermic dropping) in treatmant group were higher than the control group,but the treatment was not discontinued.Conclusions:It is suggested that this method is an effective therapy for superficial tumors.
出处
《中华理疗杂志》
1997年第4期227-228,共2页
Chinese Journal of Physical Therapy