摘要
目的探讨机体在不同健康状态下患新型隐球菌性脑膜炎的临床特点。方法对19例平素身体健康,无任何临床疾病的新型隐球菌性脑膜炎患者进行回顾性分析,15例有不同临床疾病的新型隐球菌性脑膜炎患者作为对照。结果两组患者皆多表现头痛、发热、颈部强直等症状体征,但观察组多表现亚急性或慢性起病,剧烈头痛,颅内压力>2.94kPa者与脑脊液白细胞>5×108/L者所占比例较大,死亡率低。结论在机体健康状态较好情况下患新型隐球菌性脑膜炎多表现为亚急性或慢性起病,剧烈头痛,颅内压力显著增高和脑脊液白细胞数显著增高,死亡率低等特点。
Objective To explore the clinical characteristics of Cryptococcal neoformans meningitis （CNM） infection in patients with different health status. Methods The clinical data of 19 patients with CNM who were not suffered from other diseases, and 15 CNM patients who were suffered from various diseases as controls were retrospectively analyzed. Results Almost all patients had headache, fever, stiff neck, etc. The patients with CNM who presented subacute or chronic illness onset, had higher rates of severe headache,intracranial pressure（ 〉2.94 kPa） ,white blood cell count（ 〉5 ×10^8/L ） in the cerebrospinal fluid （CSF） and lower rates of mortality. Conclusion The patients with CNM but in good status tended to of be subacute or chronic illness onset, higher rates of severe headache, elevated intracranial pressure, white blood cell count of CSF and lower rates of mortality.
出处
《哈尔滨医科大学学报》
CAS
北大核心
2008年第5期503-505,共3页
Journal of Harbin Medical University
关键词
新型隐球菌
脑膜炎
临床特点
Cryptococcus neoformans
meningitis
clinical characteristics
