摘要
本文采用了一种新的简便方法合成了四个新型手性固定相:N-十一碳-10-烯酰-L-缬氨酰-S-α-苯乙胺(手性-S-1)、N-十一碳-10-烯酰-L-缬氨酰-R-α-苯乙胺(手性-R-1)及手性-S-2、手性-S-3。并对外消旋的α-、β-氨基酸,外消旋的α-、β-羟基酸和含手性烃基的外消旋胺进行了拆分。在四个固定相中手性-S-1对上述对映体的拆分选择性最好。
Four novel chiral stationary phases, N-undooonoyl-L-valyl-S (or R)-α-phenylethy-lamide(CSP-S-1 or CSP-R-1), CSP-S-2 and CSP-S-3, have been synthesized by a simple new method. And some racemic α- and β-amino acids, α- and β-hydroxy acids and amines with asymmetric alkyl group wore resolved. The enantioselectivity of OSP-S-1 is the best one for their separations.
出处
《化学学报》
SCIE
CAS
CSCD
北大核心
1990年第11期1127-1130,共4页
Acta Chimica Sinica
基金
国家自然科学基金
