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美丽属海绵次生代谢产物及其生物活性 被引量:3

Secondary metabolites and their bioactivities of marine sponge Callyspongia
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摘要 美丽属海绵Callyspongia sp.分布广泛,含有多种生物活性成分,如多炔、肽类、生物碱、脂肪酸、聚酮类、甾体等,其中许多化合物具有抗污浊、抗肿瘤和抗菌等多种生物活性。按化合物的结构类型简要介绍了近几十年来美丽属海绵化学成分及其生物活性的研究进展,为进一步的研究工作提供参考。 Marine sponges of genus Callyspongia are widely distributed and contain various bioactive constituents such as polyacetylenes, peptides, fatty acids, polyketide and steroids. Many of these secondary metabolites have diverse bioactivities such as antifouling, anticancer and antimicrobial activities, and become target compounds for chemical synthesis and lead optimization. This review paper describes the progress in chemical and bioactive research of this genus in recent years so as to reveal further research.
出处 《热带海洋学报》 CAS CSCD 北大核心 2008年第6期73-80,共8页 Journal of Tropical Oceanography
基金 国家自然科学青年基金项目(40706046,40006009) 中国科学院重要方向性项目(KZCX2-YW-216) 中国科学院知识创新项目(KSCX2-SW-132) 中国科学院生态系统研究网络台站研究基金 重大基础研究前期研究专项项目(2005CCA04800) 中国科学院南海海洋研究所创新课题(LYQY200303) 广东省科技计划项目(2004B60302004,2005B60301032) 广东省海洋药物重点实验室开放课题 中国科学院海洋研究所海洋生态与环境科学重点实验室开放基金项目
关键词 美丽属海绵Callyspongia sp. 次生代谢产物 生物活性 Callyspongia secondary metabolite bioactivity
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参考文献39

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二级参考文献63

共引文献26

同被引文献29

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