摘要
目的测定桂皮醛在肾气丸各拆方组水煎液中的含量,分析肾气丸"阴中求阳"配伍对桂皮醛含量的影响。方法将肾气丸组方药物拆方分为补阳组-1、补阳组-2、补阴组-1、补阴组-2、阴阳双补组-1和阴阳双补组-2(即肾气丸全方),采用高效液相色谱法测定各肾气丸拆方组水煎液中桂皮醛的含量。结果阴阳双补组-2水煎液中桂皮醛含量高于补阳组-2和阴阳双补组-1,阴阳双补组-1和补阳组-2水煎液中桂皮醛含量高于补阳组-1,且都具有统计学意义。结论肾气丸"阴中求阳"配伍能增大水煎液中桂皮醛的含量,且肾气丸中的"三泻"药物(茯苓、泽泻、丹皮)也有增强此作用的趋势。
Objective To detect the content of cinnamaldehyde in decoction of each dismantled Shenqi-Pill drug group, and analyze the influence of compatibility of Shenqi-Pill by ＂reinforcing Yang from Yin＂ on the content of cinnamaldehyde in each decoction. Methods Divided the drugs of Shenqi - Pill into Invigorating Yang Group Ⅰ , Invigorating Yang Group Ⅱ , Invigorating Yin Group Ⅰ , Invigorating Yin Group Ⅱ , Invigorating Yin - Yang Group Ⅰ , Invigorating Yin-Yang Group Ⅱ （ the whole Shenqi-Pill）. And to measure the content of cinnamaldehyde in each dismantled Shenqi Pill drug decoction by using the method of high performance liquid chromatogram. Results The content of cinnamaldehyde of the whole Shenqi - Pill was higher than that of Invigorating Yang Group Ⅱ and Invigorating Yin - Yang Group Ⅰ . Meanwhile, the contents of einnamaldehyde of Invigorating yin - yang Group Ⅰ and Invigorating Yang Group Ⅱ were both higher than that of Invigorating yang Group Ⅰ . All of these possess statistical significance. Conclusion The content of einnamaldehyde of invigorating Yin-Yang groups is higher than that of the pure invigorating Yang group, and ＂san xie＂ （hoelen, alisma rhizome, moutan cortex） enhance this tendency.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2008年第11期2618-2620,共3页
Lishizhen Medicine and Materia Medica Research
基金
国家自然科学基金面上项目(No.30572295)
关键词
肾气丸
阴中求阳
桂皮醛
高效液相色谱法
Shenqi-Pill
Reinforcing Yang from Yin
Cinnamaldehyde
High performance liquid ehromatogram
