摘要
细胞因子信号传导抑制因子是对细胞因子具有负反馈调节作用的蛋白质分子,可在各种细胞因子和某些抗原的刺激下迅速表达,并通过干涉细胞因子信号传导中的JAK-STAT通路抑制进一步的信号传导。牙周病是一种多因素疾病,其发病过程涉及多种致病因素和复杂的细胞因子信号传导。下面就细胞因子信号传导抑制因子与牙周病的关系进行综述。
The suppressors of cytokine signalling (SOCS) proteins are negative regulators of cytokine signalling. They can be induced rapidly in response to cytokines and some agents, and inhibit signalling via the JAK-STAT pathway. Periodontal disease is a kind of muhifactorial disease, many pathogenic factors and complex cytokine signalling are involved in this disease. Now here is a review about the relationship between SOCS and periodontal disease.
出处
《国际口腔医学杂志》
CAS
2008年第6期654-656,659,共4页
International Journal of Stomatology