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选择性瘦素抵抗:高血压发病的新机制 被引量：6

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摘要 肥胖症发病率在全世界范围内不断增长，已经成为了一个严重威胁人类健康的问题。肥胖症患者罹患糖尿病、肾功能衰竭及心血管疾病的危险性大大增加。临床研究和动物实验已经证实，肥胖症与高血压病的发生发展密切相关。已有越来越多的研究证据表明，内脏型肥胖是高血压和心血管疾病最重要的危险因素。而人们对于联系肥胖症和心血管疾病的机制却知之甚少。
作者 王伊南 邹大进
机构地区 第二军医大学附属长海医院内分泌科
出处 《中华高血压杂志》 CAS CSCD 北大核心 2008年第11期967-969,共3页 Chinese Journal of Hypertension
关键词 高血压病 发病率 瘦素抵抗 肥胖症患者 心血管疾病 肾功能衰竭 内脏型肥胖 世界范围
分类号 R544.1 [医药卫生—心血管疾病] R589.2 [医药卫生—内分泌]
  • 相关文献

参考文献32

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二级参考文献21

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同被引文献93

  • 1中国防治认知功能障碍专家共识专家组.中国防治认知功能障碍专家共识[J].中华内科杂志,2006,45(2):171-173. 被引量：568
  • 2刘正娟,刘金.瘦素及其受体的生物学特性[J].国际儿科学杂志,2006,33(5):341-343. 被引量：8
  • 3姜兰斌,韩维权.血清瘦素水平与冠状动脉病变的关系[J].微循环学杂志,2007,17(1):36-37. 被引量：3
  • 4汪晓洲,马爱群,王军,张炜.正常大鼠中枢神经瘦素受体的分布[J].中华高血压杂志,2007,15(1):66-69. 被引量：4
  • 5Francischetti EA,Genelhu VA.Obesity-hypertension:an ongoing pandemic[J].Int J Clin Pract,2007,61(2):269-280.
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  • 10Lam QL,Lu L. Role of leptin in immunity. Cell Mol Immunol, 2007,4:1-13.

引证文献6

二级引证文献29

中华高血压杂志
2008年 第11期

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