摘要
运用fMRI探讨外关穴配伍支沟穴皮部浅刺激和常规深度刺激激活脑功能区的特点。方法:8名健康志愿者先后进行外关穴配伍支沟穴皮部浅刺激和常规深度刺激,运用GE公司1.5T超导核磁共振系统完成脑部fMRI扫描,基于感兴趣区(ROI)观察局部脑区的功能变化,用统计学方法比较激活几率、激活点数和激活强度。结果:两种方法对左右不同脑区都有不同程度的激活,统计表明无显著性差异(P>0.05);但有趋势表明,皮部浅刺相对集中激活额叶,常规针刺相对集中激活枕叶、小脑和基底节区。结论:外关穴配伍支沟穴皮部浅刺激和常规深度刺激对脑功能区的激活没有显著差异,但二者有着作用倾向的不同。表明两种层次的针刺刺激产生的效应,与脑部整合作用相关。
Objective： To compare the different activation on cerebral functional regions between cutaneous stimulation and routine needling in Waiguan （ SJ5 ） and Zhigou （SJ6） by fMRI. Methods ： Eight volunteers received 2 times stimulation of cutaneous or routine needling in S J5 and S J6, and reeeived the cerebral fMRI scan under the different states by GE 1.5T superconducting magnetic resonance imaging system. The cerebral activated states of different ROIs were compared between the two different stimulating methods. Results： Two needling methods both activated bilateral cerebral areas in different degree, and the activations had not any different between the superficial and deep needling （P 〉 0. 05）. But there was a trend that cutaneous needling concentrated activated the left frontal lobe, while routine needling concentrated activated the occipital lobes, cerebellum and basic ganglion. Conclusion： The cerebral activating states in different ROIs under the stimulations of cutaneous or routine needling in S J5 and SJ6 had not any differences, but there was a different acting trend, which indicated that the clinical functions of needling SJ5 and SJ6 had a close relationship with the comprehensive adjusting of the brain.
出处
《云南中医学院学报》
2008年第6期44-47,共4页
Journal of Yunnan University of Traditional Chinese Medicine
基金
国家重点基础研究发展计划(973计划)资助课题(No.2006CB504505)
国家自然科学基金重大研究计划课题(No.90709027)
