摘要
目的综述HBV的基因型研究新进展。方法参阅近年来国内外公开发表的文献,对HBV基因型研究新进展进行综述。结果迄今为止,已经发现HBV有A、B、C、D、E、F、G、H8个基因型.根据不同的病毒学和传染病学特质,一些基因型再分成24个基因亚型。HBV累计的点突变形成不同的基因型,HBV的自然变异对于疾病的临床转归影响成为国际研究的热点。结论基因型的提出为肝炎病毒的研究开辟了新的领域。
Objective To summary new progress of the study to hepatitis B virus genotypes .Metheds To summary new progress of the study to hepatitis B virus genotypes referring to published at home and abroad.Result Up to now, A-H 8 genetypes have been found, Most geuetypes are now divided into subgenotypes with distinct virological and epidemiological propertieso Gene mutations of HBV has formed different Genotypes o Influence of hepatitis B virus'natural gene mutations to result of hepatitis B has become focus of international institute .Conclusion Genotpying has opened up a new field to study hepatitis B virus.
出处
《疾病监测与控制》
2008年第12期761-763,共3页
Journal of Diseases Monitor and Control