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高龄患者急性心肌梗死的介入与药物治疗对比研究 被引量:2

Comparative study of the treatment of percutaneous coronary intervention and medication in elderly patients with acute myocardial infarction
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摘要 目的:评价直接经皮冠状动脉介入治疗(PCI)对高龄急性心肌梗死(AMI)患者的临床疗效。方法:分析我院2003年2月~2008年1月诊断为AMI且年龄>75岁的132例患者的临床资料.并进行6个月随访。其中分为直接PCI治疗组与药物治疗组。比较两组临床特征以及住院与随访期间不良心血管事件(再发心绞痛、心肌梗死、猝死)的发生率。结果:直接PCI治疗组62例患者住院死亡7例、再发心绞痛及心肌梗死2例、平均住院12.4±5.2d,随诊期间再发心绞痛9例、心肌梗死4例、猝死2例。药物治疗组70例患者住院死亡14例、再发心绞痛及心肌梗死8例、平均住院20.1±7.4d,随诊期间再发心绞痛20例、心肌梗死11例、猝死5例。结论:高龄AMI行介入治疗者住院及随访期间病死率和主要不良心脏事件发生率显著低于药物治疗者.临床疗效良好。 Objective:To evaluate the effectiveness of primary percutaneous coronary intervention (PCI)in the elderly patients with acute myocardial infarction (AMI).Methods:A total of 132 patients with acute myocardial infarction aged over 75 years were retrospectively Studied.The patients were divided into primary PCI group(n= 62)and medication group(n=70).The basic characteristics and major adverse cardiac events(MACE)including recurrent angina,myocardial infarction and sudden cardiac death during hospitalization and follow-up after discharge were compared between the two groups.Results:In primary PCI group 7 patients died,2 patients suffered from angina pectoris relapse and myocardial infarction.The mean hospitalization day was (12.4±5.2)days. Angina pectoris (9 patients) ,myocardial infarction (4 patients)and sudden death (2 patients)occurred in the follow-up time.In medication group 14 patients died,8 patients suffered from angina pectoris relapse and myocardial infarction.The mean hospitalization day was(20.1±7.4)days.Angina pectoris(20 patients),myocardial infarction(11 patients)and sudden death(5 patients)occurred in the follow-up time.Conclusion:The mortality and the rate of relapse were significantly lower in primary PCI group than in medication group.Primary PCI in the elderly patients with AMI is effective.
出处 《中日友好医院学报》 2008年第6期337-339,共3页 Journal of China-Japan Friendship Hospital
关键词 老年人 急性心肌梗死 直接经皮冠状动脉介入治疗 主要不良心血管事件 elderly acute myocardial infarction primary percutaneous coronary intervention major adverse cardiac event
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