摘要
目的分析2002-2007年江苏省疑似预防接种异常反应(AEFI)的发生特征,评价AEFI监测系统运转情况,预防接种服务质量和疫苗的安全性。方法通过江苏省AEFI月常规报告系统和中国免疫规划监测信息管理系统收集的2002-2007年江苏省报告的AEFI个案数据,采用描述性方法对相关指标进行流行病学分析。结果全省5年来共收到AEFI个案5091例,AEFI反应分类以一般反应最为多见,有3292例个案,占总个案数的64.66%;异常反应有1734例,占34.06%;偶合症有38例,占0.75%;实施差错事故有13例,占0.25%;心因性反应有5例,占0.10%;不明原因与不详各有2例,分别占0.04%。涉及疫苗30种,其中报告最多的是百白破疫苗,发生AEFI的有1563例,占30.70%。结论通过监测数据表明,全省的AEFI监测系统运转正常;社会上所使用的疫苗安全性和预防接种服务质量良好;但AEFI个案报告、调查的及时性有待进一步提高;要加强对临床医生在AEFP诊断、分类及处理等相关知识的培训工作,确保AEFP监测数据的质量。
Objective To analyze the occurrence features of adverse effects following immunization （AEFI） in Jiangsu Province from 2002 to 2007, and to evaluate the implementation of AEFI surveillance system, the safety of vaccines, and the quality of immunization services. Methods The AEFI data of Jiangsu Province during the period of 2002--2007 were col- lected through the AEFI Monthly Routine Report System of Jiangsu Province and the China Information System for national immunization program （NIP）. The descriptive methodology was used in this study. Results Totally 5,091 AEFI cases were reported during a .5 - year period. There were 3,292 cases with vaccine general reactions which accounted for 64.66% among AEFI classification, 1,734 cases with vaccine paradoxical reaction （34.06%）, 38 cases with coincidental illness （0.7.5 % ）, 13 cases with operation error （0.25 % ）, 5 cases with psychological reaction （0.10 % ）, and 2 cases with unknown reason （0.04 % ）. There were 30 kinds of vaccines involved in AEFI cases, 1,563 AEFI. cases induced by DPT vaccine, which accounted for 30.70%. Conclusions According to the data of surveillance, the AEFI surveillance system of Jiangsu Province works in good condition. The safety of vaccines and the quality of immunization service are fine in clinics. However, the timeliness of surveillance needs to be further improved. To make sure of the quality of surveillance data of AFEI, training about diagnosis, classification and treatment of AEFI should to be strengthened in clinical doctors.
出处
《实用预防医学》
CAS
2008年第6期1796-1800,共5页
Practical Preventive Medicine
关键词
疑似预防接种异常反应
监测
评诂
Adverse effects following immunization
Surveillance
Evaluation
